An updated review on therapeutic strategies in NSCLC harbouring HER2 alterations.ESMO Open. 2021 Oct; 6(5): 100260. [3] KrishnamurtiU, Silverman JF. HER2 in breast cancer: a review and update. Adv Anat Pathol.2014;21(2):100-107. doi:10.1097/PAP.0000000000000015 [4]Li B.T., Ross D....
【3886】Breast Cancer | HER2低表达与HER2零表达早期乳腺癌新辅助化疗后病理学完全缓解和预后差异 随着抗体药物偶联物(ADCs)的研发,HER2 低表达人群逐渐备受关注。目前,HER2 低表 达乳腺癌的生物学特征尚不十分明确,HER2 低表达与 HER2 ...
[8]Pérez-García JM, Batista MV, Cortez P, et al. Trastuzumab Deruxtecan in Patients with Central Nervous System Involvement from HER2-Positive Breast Cancer: The DEBBRAH Trial. Neuro Oncol. 2022 May 26:noac144. [9]Epaillard N, Lusque A , Pistilli B, et al. Antitumor activity of tra...
这部分患者的HER2水平介于HER2阴性和HER2过表达之间,他们的治疗和预后一直不明确。2023年4月,Breast Cancer Research and Treatment杂志发表了一篇题为HER-2 low status in early-stage invasive lobular carcinoma of the breast: associate...
[4]Müller V, Bachelot T, Curigliano G, et al. Expert consensus on the prevention of brain metastases in patients with HER2-positive breast cancer. Cancer Treat Rev. Published online November 17, 2024.[5]Gori S, Puglisi F, Moroso S, et al. The HERBA Study: A Retrospective Multi-...
[1]Ripperger T, Gadzicki D, Meindl A, et al. Breast cancer susceptibility: current knowledge and implications for genetic counselling. Eur J Hum Genet. 2009;17(6):722 31. [2]Malone KE, Daling JR, Doody DR, et al. Prevalence and predictors of BRCA1 and BRCA2 mutations in a population...
2023年，《Nature Communications》杂志发表了一篇题为《Comprehensive genomic characterization of HER2-low and HER2-0 breast cancer》的文章，为我们提供了对这一问题深入的见解。研究方法 本研究旨在深入分析HER2低表达（HER2-low）和HER2-0（免疫组化[IHC] 0）乳腺癌的基因组特征，并探讨两者是否存在显著的分子...
相关论文于当地时间8月22日在线发表于国际知名期刊《自然-通讯》（Nature Communications），题为“Molecular features and clinical implications of the heterogeneity in Chinese patients with HER2-low breast cancer”，这也是该研究在2022年圣安东尼奥乳腺癌大会（SABCS）入选亮点讨论后的正式见刊。邵志敏、江一舟团队...
Brain metastases in breast cancer; natural history, prognostic factors and outcome. J Neurooncol. 1993 Feb;15(2):165-74. [4] Witzel I, Laakmann E, Weide R, et al. Treatment and outcomes of patients in the brain metastases in breast cancer network registry. Eur J Cancer. 2018 Oct:102...
相关论文于当地时间8月22日在线发表于国际知名期刊《自然-通讯》(Nature Communications),题为“Molecular features and clinical implications of the heterogeneity in Chinese patients with HER2-low breast cancer”,这也是该研究在2022年圣安东尼奥乳腺癌大会(SABCS)入选亮点讨论后的正式见刊。