Tacke F. Relevance of hepatitis B virus genome variability in organ transplantation. Hepat Mon - Amini-Bavil-Olyaee, Trautwein () Citation Context ...cs of viral production and clearance; lack of a proofreading mechanism during reverse transcription, which creates a large HBV quasispecies pool, ...
hepatitis B,infectious diseaseof theliver, the causative agent of which is known ashepatitis B virus(HBV). The course and severity ofillnessassociated with HBV infection varies widely. Some persons are asymptomatic, for example, whereas others experienceacuteillness and eliminate the virus from the ...
Efficacy In Neonates With Peripartum Exposure To Hepatitis B The protective efficacy of three 5 mcg doses of RECOMBIVAX HB has been demonstrated in neonates born of mothers positive for both HBsAg and HBeAg (a core-associated antigenic complex which correlates with high infectivity). In a clinica...
Hepatitis B vaccine (Engerix-B, Recombivax HB) is given to children, adolescents, and adults to prevent the hepatitis B virus. Side effects of Energix-B and Recombivax HB include, dizziness, fever, diarrhea, fatigue, and headache.
Human Hepatitis B virus (HBV) is the prototype member of the family Hepadnaviridae, which includes a variety of avian and mammalian viruses that share similar genomic organization, organ trophisms, and a unique strategy of genome replication. Hepatitis B virus can be further classified into eight...
The targets of T cell and B cell epitopes in the HBsAg are concentrated in the hydrophilic loops between the α-helices that harbor more variable aa residues. That includes the major hydrophilic region (MHR, aa 99–160), which contains a conformational B cell epitope cluster. In addition, ...
Moreover, depending on the degree of prematurity and the associated degree of maladaptation to the extrauterine life of other organ systems, preterm infants require substantial and prolonged medical support. Together, the unfit organs attempting to sustain life and adverse effects of such medical ...
Careful attention should be given to medications or compounds, which can have adverse effects in patients with abnormal liver function (for example, acetaminophen [Tylenol and others], alcohol, etc.). Only those medications that are considered necessary should be administered since the impaired liver...
Hepatitis B (HepB) vaccines are composed of HBsAg adsorbed to an adjuvant ofaluminum hydroxideor aluminum hydroxyphosphate sulfate.148,149HBsAg elicits development of the neutralizing antibody, anti-HBs, which confers protection from infection. Plasma-derived vaccines were manufactured from HBsAg purified...
which carry the surface antigen gene of the hepatitis B virus. The HBsAg expressed in the cells is purified by several physicochemical steps and formulated as a suspension of the antigen adsorbed on aluminum hydroxide. The procedures used to manufacture ENGERIX-B result in a product that contains...