(IACUC) and be conducted in accordance with applicable law including but not limited to the Animal Welfare Act and to the extent applicable animal facilities must meet the standards of the American Association for Accreditation of Laboratory Animal Care (AAALAC) and the Association for Assessment ...
We aimed to identify the potential diagnostic markers and associated molecular mechanisms based on programmed cell death (PCD)-related genes in patients with heart failure (HF). Three HF gene expression data were extracted from the GEO database, includin
Left ventricular remodeling in heart failure: current concepts in clinical significance and assessment J Am Coll Cardiol Img, 4 (2011), pp. 98-108 View PDFView articleView in ScopusGoogle Scholar 4 J.M. Griffin, B.A. Borlaug, J. Komtebedde, et al. Impact of interatrial shunts on invasiv...
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Heart failureClinical trial designHealth technology assessmentRegulatory scienceA workshop was organized by the Agenzia Italiana del Farmaco (AIFA) to discuss unmet needs and ways forward in the development of medicines in heart failure, their rationale, and cost-effective use. An integrated, ...
Myocardial fibrosis assessment by semiquantitative, point-counting and computer-based methods in patients with heart muscle disease: a comparative study. Histopathology. 2001;38(4):338–43. Article CAS PubMed Google Scholar Winters J, von Braunmuhl ME, Zeemering S, Gilbers M, Brink TT, Scaf...
c, Assessment of the average number of vessel-like structures (VL) present on paraffin sections of HFOs (front view). Left: Representative image of an HFO paraffin section stained for CD31, in which the VLs are marked with asterisks. Right: Number of VLs per 1 mm² IC area. Data ...
Heart failure (HF) has been recognized as a global pandemic with a high rate of hospitalization, morbidity, and mortality. Although numerous advances have been made, its representative molecular signatures remain largely unknown, especially the role of genes in HF progression. The aim of the presen...
The repeatability and robustness of the proposed subtypes were further quantitatively assessed in a validation cohort using the nearest template prediction (NTP) algorithm. NTP has been widely used for signature gene expression-based typing and confidence assessment29,30. Additionally, we downloaded 4 ...
For a healthy heart, the cloud of points presents a comet shape oriented along the line of identity; the cardiac heart-failure dynamics are characterized by a stretched elliptical-shaped cloud of points also along the line of identity. In the atrial fibrillation (AF) case, the cloud of ...