Lymphatic map- ping and sentinel lymphadenectomy for 106 head and neck lesions: contrasts between oral cavity and cutaneous malignancy. Laryngoscope 2006;112(3, Part 2, Suppl 109):1-15.Civantos FJ, Moffat FL and Goodwin WJ: Lymphatic mapping and sentinel lymphadenectomy for 106 head and neck ...
lymph node; PD-1: programmed cell death protein 1; PDGRFA: platelet-derived growth factor receptor alpha; p-EMT: partial epithelial-to-mesenchymal transition; scDNA-seq: single cell DNA sequencing; scRNA-seq: single cell RNA sequencing; TCF7: transcription factor 7; TCR-seq: T cell...
For pancreatic cancer, [18F]FDG PET showed positivity rates of 0.93 (95% CI: 0.76-1.00) and 0.46 (95% CI: 0.23–0.69) for primary cancer and lymph node metastases, respectively. In comparison, [68Ga]Ga-FAPI-04 PET showed similar positivity rates of 1.00 (95% CI: 0.94-1.00) and ...
The heat map analysis revealed significant differences in the overall correlation patterns of immune cell types between two distinct sample groups, referred to as C1 and C2 (Fig. 5A, B). In the C1, eosinophils exhibited the highest positive correlation with mast cells, T follicular helper cells...
From these significantly changed expressions the analysis finds 26 cancer-related (ACAT1, ARPC1A, ATP5J, CANX, DDX39B, DDOST, EXT1, FGFR1, GOLPH3, MAGT1, MAPK8IP3, MAT2A, MMADHC, P4HB, PDK4, RHOA, SCARB2, SDHB, SDHD, SEC63, SSR1, SSR3, TM9SF2, TMED2, TRAM1, ZMPSTE24)...
a localized region can be cropped out to focus on segmenting the fine boundaries in a zoom-in fashion. The detection was implemented using a simple yet effective heat map regression approach and the heat map labels were generated at each organ center using a 3D Gaussian kernel44,45. Letf(·...
The ten lesions include several with diagnostic cells which look similar to the histiocytes of a reactive inflammatory ulcer, including Rosai–Dorfman disease, reticulohistiocytoma, Langerhans cell histiocytosis, and traumatic ulcerative granuloma. Other lesions, such as EBV-positive mucocutaneous ulcer, ...
Lymph node and/or distant metastases were present in 17% at presentation. Patients received a combination of surgery, chemotherapy, and radiotherapy. The 10-year event-free and survival rates were 53.1%±7.3% and 63.2%±7.1%, respectively. Features associated with inferior survival included high ...
1/59 (1.6%) , 28 patients with negative lymph nodes and 31 patients without lymph node sampling, developed distant metastasis. Clinical factors associated with metastasis were young age (mean 35 years, p=0.02), female gender, and carotid body location, although the age is the only parameter ...
The poor prognosis of head and neck cancer (HNC) is associated with metastasis within the lymph nodes (LNs). Herein, the proteome of 140 multisite samples from a 59-HNC patient cohort, including primary and matched LN-negative or -positive tissues, saliva, and blood cells, reveals insights ...