To improve the directionality of the immobilisation, a binding site blocker (60 μM JW4780, a bulky CsA analogue) was added to the diluted protein solutions. This mixture was allowed to stand at room temperature for 10 min prior to set-up in the injection rack. Data was collected on...
A hepatitis C virus (HCV) plasmid vaccine was constructed, based on class II-associated invariant chain peptide (CLIP) substitution which endogenously targets HCV non-structure protein 3 (NS3) CD4+ T helper 1(Th1) epitope (1248AA-1261AA) to major histocompatibility complex (MHC) class II antig...
The SAR study indicated that the introduction of electron-donating substitutions on the benzene ring was helpful for the anti-HCV activity, and the unsaturated 11-side chain might not be favorable for the activity. This study provided powerful information on further strategic optimization and ...
The protein complexes were screened for crystallization in sitting drops using the Phoenix robot (Art Robbins) and commercial screening solutions. Crystallization droplets consisted of 0.2μL protein and 0.2 μL reservoir at 18 and 4 °C. The 5B3.v3/E2 complex crystallized after 2 days with 0.1...
Example 11 Preparation of the Compound of Formula (XI) 11.49 g (34.58 mmol) of the compound of formula (VIII) and 9.52 g (36.30 mmol) triphenylphosphine were added to a solution of the compound of formula (VII) in toluene (34.58 mmol compound of formula (VII) for 184.86 g solution). ...
HPE ProLiant ML30 Gen10 server is a powerful yet affordable tower server designed for small offices, remote and branch offices to run on-premise and Hybrid Cloud solutions, delivering enterprise-class performance, security, reliability, and expandability at a lower cost. Just a ...
Our company not only provides customers with high-quality products but also offers first-class services as well as effective support and solutions. In recent years, our machines are sold domestically and overseas such as Arab, India, Russia, Mongolia, Central Asia, ...
6. Different shipping solutions7. Stable space promise even in peak seasonBefore inquiry, providing your cargo details as following will be highly appreciated. 1. Name of commodity:2. Total Gross Weight of commodity:3. Total Volume of commodity:4. Port of loading (PO...
In line with the business tenet of "piping solutions expert" and the mission of "making work easy and efficient", we have independently developed and produced a series of products that customers love. Our product series mainly include pipe-cutting machines, pipe-weldi...
but not limited to, capsules, tablets, aqueous suspensions or solutions. In the case of tablets for oral use, carriers that are commonly used include lactose and corn starch. Lubricating agents, such as magnesium stearate, are also typically added. For oral administration...