A hepatitis C virus (HCV) plasmid vaccine was constructed, based on class II-associated invariant chain peptide (CLIP) substitution which endogenously targets HCV non-structure protein 3 (NS3) CD4+ T helper 1(Th1) epitope (1248AA-1261AA) to major histocompatibility complex (MHC) class II antig...
The SAR study indicated that the introduction of electron-donating substitutions on the benzene ring was helpful for the anti-HCV activity, and the unsaturated 11-side chain might not be favorable for the activity. This study provided powerful information on further strategic optimization and ...
P670. Autoimmune hepatitis type 2 and HCV infection: Study of HLA-class II antigensautoimmune hepatitis type 2 and hcv infection: study of hla-class ii antigens.doi:10.1016/0198-8859(96)85365-1A JuradoB CárdabaP JaraL HierroP Palomino...