The second aim of the study was to determine the clinical meaning of an improvement in risk scores during antiviral therapy. For both the GAG-HCC and CU-HCC scores, patients who had high risk scores at baseline and low risk scores 2 years after entecavir treatment had their HCC incidence re...
We evaluated several electronic databases, PubMed (US National Library of Medicine,http://www.ncbi.nlm.nih.gov/pubmed), Scopus (Elsevier,http://www.scopus.com/), Web of Science (Thomson Reuters,http://apps.webofknowledge.com/) and Google Scholar (https://scholar.google.it/), using as ...
miRNAs are considered promising non-invasive biomarkers. Serum represents the major source of biomarkers, being readily accessible for many analytical tests. Recently, whole blood has drawn increasing interest in biomarker studies due to the presence of
In a separate Phase 3 trial of YERVOY 3 mg/kg, severe to life-threatening immune-mediated endocrinopathies (requiring hospitalization, urgent medical intervention, or interfering with activities of daily living; Grade 3-4) occurred in 9 (1.8%) patients. All 9 patients had hypopituita...
(MS), and abnormal accumulation of lipids in the liver compared to control mice. A short-term application of the Western diet (WD) significantly worsened the phenotype and accelerate HCC development. Importantly, we found that metformin as therapeutic approach significantly attenuated MAFLD phenotype ...