View Proteintech's new GSK3 signaling pathway poster. GSK3 (Glycogen Synthase Kinase-3) is a signaling mediator involved in a variety of different signaling pathways including WNT, growth factors, insulin, and Hedgehog pathways. Browse more posters at pt
B-Cell Development Pathway B-Cell Receptor Complex BMP 通路 Bone Biology Pathways Cancer Biology Pathways Cancer Immunoediting CCR5 Pathway in Macrophages CD4 and CD8 T-Cell Lineage Cell Cycle & Proliferation Pathways Intrinsic and Extrinsic Pathway...
11LustigB,BehrensJ.TheWntsignalingpathwayanditsrolein tumordevelopment【J].JCancerResClinOncol,2003,129(4): 199-221 12BijurGN,JopeRS.Glycogensynthasekinase 一3betaishighly activatedinnucleiandmitochondriafJ】.Neuroreport,2003,14 f181:2415—2419 ...
Keywords: Triple-negative breast cancer (TNBC), Epithelial-mesenchymal transition (EMT), Cancer stem cells (CSCs), Glycogen synthase kinase β (GSK3β), Wnt signaling Background Breast cancer is a leading cause of cancer-related death among women [1, 2]. In the USA, one in eight women ...
The coordination of metabolic networks in malignant cells is dependent on the collaboration with cellular signaling pathways. Glycogen synthase kinase 3 (GSK3) lies at the convergence of several signaling axes, including the PI3K/AKT/mTOR, AMPK, and Wnt pathways, which influence cancer initiation, ...
The Wnt signaling pathway is identified as one of the main disrupted pathways in Colorectal cancer (CRC). Results from studies focusing on this route will aid greatly in the detection and treatment of CRC. MicroRNAs (MiRs), particularly MiR-490, has emerged as key regulator of gene expression...
Wnt signaling in cell adhesion, development, and colon cancer Activating the canonical Wnt pathway is a driving force in many human cancers, especially colorectal, hepatocellular, and mammary carcinomas. Wnt causes the... N Tejeda‐Muoz,K Mei - 《Iubmb Life》 被引量: 0发表: 2024年 The regu...
A key member of the Wnt intracellular pathway is GSK-3, a negative regulator of β-catenin (47, 54) that can phosphorylate it at an amino-terminal site (Yost et al. 1996). Mutations in the serine and threonine residues at this site prevent the ubiquination and degradation of β-catenin...
Human embryonic and induced pluripotent stem cells are self-renewing pluripotent stem cells (PSC) that can differentiate into a wide range of specialized cells. Basic fibroblast growth factor is essential for PSC survival, stemness and self-renewal. PI3K
The established association between Alzheimer's disease (AD) and compromised neural regeneration is well-documented. In addition to the mitigation of apoptosis in neural stem cells (NSCs), the induction of neurogenesis has been proposed as a promising th