of sodium glucose transporter-2 inhibitor (SGLT2i) as compared to either DDP4i or GLP1-RA22,23,24,25, however, there have been no prior studies to our knowledge examining direct cross-comparison of healthcare utilization between use of DDP4i and GLP1-RA in CKD in the United States. ...
In the MAD cohorts, the 140 mg dose Q4W resulted in a mean percent BW change of −2.0% at day 7 and −7.4% after three doses at day 78. The highest MAD dose of 420 mg Q4W resulted in a BW change of −4.9% at day 7 and −14.5% by day 85. In comparison, the...
Comparisons were made between fasting value at start of treatment to fasting value on Day 12 of treatment and comparison of maximum (peak) value on Day 12 vs. at treatment allocation with fasting value before treatment as covariate. Values of the area under the curve (AUC) of serum GLP-1 ...
It has been 5 years since we first learned that empagliflozin can save lives and substantially reduce cardiovascular (CV) risk in patients with type 2 diabetes (T2D) and CV disease (CVD) [1]. Subsequently, various cardiovascular and renal benefits have been demonstrated for empagliflozin and othe...
Comparisons were made between fasting value at start of treatment to fasting value on Day 12 of treatment and comparison of maximum (peak) value on Day 12 vs. at treatment allocation with fasting value before treatment as covariate. Values of the area under the curve (AUC) of serum GLP-1 ...
Comparison of the long-term effects of liraglutide and glimepiride monotherapy on bone mineral density in patients with type 2 diabetes. Endocr. Pract. Off. J. Am. Coll. Endocrinol. Am. Assoc. Clin. Endocrinol. 2016, 22, 406–411. [Google Scholar] [CrossRef] Iepsen, E.W.; Lundgren, ...