Odili, S.,Li, C., et al. (2007). Glucokinase thermolability and hepaticregulatory protein binding are essential factors for predicting theblood glucose phenotype of missense mutations. J.Biol. Chem. 282,13906–13916.
GK regulates blood glucose, via its effects on glucose stimulated insulin secretion (GSIS) from the β-cell, and hepatic glucose utilisation. In man, heterozygous loss of function mutations cause maturity onset diabetes of the young 2. In this study we generated GK [sup +/-] mice and ...
The On Call® GK Dual is a high-performance device providing the ability to test both blood glucose and ß-ketones on the same meter. Both, the On Call® Chosen and On Call® Advanced test strips are compatible for use with the On Call® GK Dual for glucose testing. The On Ca...
Effect of recombined human glucagon-like peptide-1 on body weight,blood glucose metabolism and β cell function and mass inGKrat; 重组人胰高糖素样多肽-1对GK大鼠体重、糖代谢、β细胞功能及团块量的影响 2. Effect of Glimepiride on isolatedGKrat heart myocardial protection afforded by ischemic precon...
However, in all human studies, GKAs effectively lowered blood glucose, but at the expense of an increased risk of hypoglycemia. Other liabilities like loss of efficacy with time and increase in blood pressure or triglyceride levels have been reported with different molecules. To avoid hypoglycemic ...
Monitoring blood glucose level is essential for those who live with diabetes. The KETO MOJO GK+ is a smart kit that comes with everything you need to get
Conclusions All segments of small intestine in GK rats showed bad effects on blood glucose control after injection of glucose. However, during short time intervals (2, 15, 45 min after injection), effect of middle segment of small intestine on blood glucose control was the best, effect of ...
butalso reducedglycemic-loadindiabeticratsafteroralglucose. Conclusion:Timosaponinimprovedtheglucosetoleranceandremarkablydecreasedthe blood-glucoseinspontaneousdiabeticGKrats. Keywords:timosaponin;GKrat;blood-glucose;theglucosetolerance GK大鼠是1973年由Goto及其同事通过Wistar近亲杂交而筛选出的非肥胖型自发性 型糖尿病...
The rise in blood glucose and lipid levels contribute to the development of diabetic nephropathy. Besides, increased activity of Na + K + -ATPase further damages the function of renal tubules. The increased NO leads to glomerular hyperperfusion and hyperfiltration. These factors also accelerate the...
TC，LDL-C and Liver-TG were increased significantly，Ins was decreased. After drug treatment，in test group，the blood glucose，HbAlc，TC，LDL-C，Liver-TG were significantly decreased on different levels. Conclusion ：FufangHuanglian Jiangtang Tablet can significantly decrease the blood glucose，Hb...