Mapping contigs using CONTIGuator Obtaining bacterial genomic sequences has become a routine task in today's biology. The emergence of the comparative genomics approach has led to an increa... M Galardini,A Mengoni,M Bazzicalupo - 《Methods Mol Biol》 被引量: 7发表: 2015年 加载更多来源...
vghas a number of tools to support transcriptomic analyses with spliced graphs (i.e. graphs that have annotated splice junctions added as edges into the graph). These edges can be added into an existing graph usingvg rna. We can then perform splice-aware mapping to these graphs usingvg mp...
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In addition, gold standard assembly results and mapping results were provided by CAMI, which could be the input file of genome binning tools. Gold standard of assembly and binning can minimize chimera errors caused by assembly tools and reduce biases in evaluation of the performance of each ...
To this end, locus-specific epigenome mapping tools and technologies are expected to greatly empower researchers to elucidate functional roles of chromatin modifications. Such tools will enable investigating some of the long-standing questions of chromatin biology such as the causal relationship between ...
Reference: Pucker B. Mapping-based genome size estimation. bioRxiv 607390; doi:https://doi.org/10.1101/607390 Releases1 v0.4 of MGSELatest Apr 11, 2019
Tools that lack precision cannot scale to the needs of modern software development. Inaccurate and/or incomplete data will leave organizations to deal with vulnerabilities, licensing, and other quality issues that lead directly to higher costs and reduced innovation. With precise identification on your...
Also, these analytical tools extend the scope of analysis beyond a single family, and in fact may work most efficiently when applied to very many virus families. When compared to the results of the current expert-driven taxonomy, these tools were shown to have both high sensitivity and ...
. Most existing tools for comparative assembly developed to date can only exploit a single ‘reference’ to assemble against [4,13]. Through the creative use of ALLMAPS, we can greatly expand the types of evidences that can be applied to a genome assembly even in situations where mapping ...
Because robust identification of mutational excess requires an accurate model of the neutral mutation rate, computational tools that carefully model somatic mutation rates are central to locating additional cancer drivers. This task is made challenging by the highly variable and tissue-specific patterns of...