Evolutionary genetics and genetic variation of haplodiploids and X-linked genes. Annual Review of Ecology and Systematics 28:55-83.Hedrick, P.W.; Parker, J.D. 1997: Evolutionary genetics and genetic variation of haplodiploids and x-linked genes. Ann. Rev. Ecol. Syst. 28:55-83....
Here we report mutations in two X-linked genes encoding neuroligins NLGN3 and NLGN4 in siblings with autism-spectrum disorders. These mutations affect cell-adhesion molecules localized at the synapse and suggest that a defect of synaptogenesis may predispose to autism. This is a preview of ...
Genetics is the branch of science concerned with genes, heredity, and variation in living organisms. It seeks to understand the process of trait inheritance from parents to offspring, including the molecular structure and function of genes, gene behaviour in the context of a cell or organism (e...
The role of X-inactivation is often ignored as a prime cause of sex differences in disease. Yet, the way males and females express their X-linked genes has a major role in the dissimilar phenotypes that underlie many rare and common disorders, such as intellectual deficiency, epilepsy, congeni...
Genes for individualism and entrepreneurialism may affect countries' unemployment rates How do you perceive privacy? How individualistic are you? Advertisements European cultures European vs American culture & society (1) The French character (2) The Belgian character ...
Furthermore, X-linked multicopy genes exhibit a similar degree of expression as autosomal genes. Thus, not only is the mouse X chromosome enriched for spermatogenesis genes functioning before meiosis, but in addition, ∼18% of mouse X-linked genes are expressed in postmeiotic cells. This is ...
(1961). Gene action in the X-chromosome of the mouse (Mus musculus L.). Nature 190372. Google Scholar Ohno, S. (1967). Sex Chromosomes and Sex-Linked Genes, Springer, New York, 192 pp. Google Scholar Ohno, S. (1973). Ancient linkage groups and frozen accidents. Nature 244259. ...
Like autosomal recessive conditions, the X-linked conditions screened do not overlap across the molecular testing laboratories. In fact, some carrier panels on the market contain genes associated with conditions that have a prevalence of 1 in 3,500 while others a condition with a prevalence less ...
One method is upregulation of X-linked genes [16]. In humans, one of the female copies of the X chromosome is silenced during embryogenesis to achieve dosage compensation during a process called X chromosome inactivation [6] (Fig. 1B). The X-linked gene XIST is expressed from the ...
An abundance of X-linked genes expressed in spermatogonia. Nature Genet. 27, 422–426 (2001). Article CAS PubMed Google Scholar Khil, P. P., Smirnova, N. A., Romanienko, P. J. & Camerini-Otero, R. D. The mouse X chromosome is enriched for sex-biased genes not subject to ...