The expression of the apoptosis-related gene BCL2L13, XAF1, and NF2 were significantly different between OA and healthy meniscus samples. The construction of a covariation network of RNA-binding proteins (RBPs) and RAS genes revealed that differentially expressed RBP genes LAMA2 and CUL4B may ...
Therefore, establishing the rule that low expression of JCHAIN help to recognize IgG-producing B cell is reasonable. For the results using the MCFS algorithm, we also recognized a low expression of JCHAIN in B cells (IgA, IgG, and memory B cells) [68,69,70]. Another gene, ICA1, as a...
DESeq [68,69] R package was used to determine differential expression of the same genes in the two samples (CT and MJ). In achieving this, two criteria were selected: one was FoldChange, which is the multiple of change in the expression level of the same gene in the two samples; the...
gene naming was often aplayground for creative scientists, leading to notorious genes like “sonic hedgehog” (yes, named forthat Sonic) and “Indy” (short for “I’m not dead yet”; a reference to the gene’s function, which can double the life span of fruit flies when mutated). ...
While 32 of these genes have not been previously linked to ASDs, one of them, SLIT3, has been associated with another neuropsychiatric disorder (Table 2). Duplications overlapping the SLIT3 gene were previously found to be overrepresented in individuals with major depressive disorder [38]. In ...
Satge D, Sasco AJ, Geneix A, Malet P (1998a) Another reason to look for tumor suppressor genes on chromosome 21. Genes Chromosomes Cancer 21: 1Satge, D., A. J. Sasco, A. Geneix, and P. Malet. 1998. Another reason to look for tumor suppressor genes on chromosome 21. Genes ...
The human TP53 gene encodes N-terminally or C-termin- ally truncated isoforms, in addition to the full-length p53 protein.17 Among those natural p53 isoforms, an N-terminally truncated Δ133p53 (which lacks the N-terminal 132 amino acids) inhibits the activity of wild-type, full-length p53...
Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by the presence of proliferative lesions throughout the body. Management of TSC is challenging because patients have a multifaceted systemic illness with prominent neurologi
There are two similar genes in the bodies of mammals.By changing the function of on gene,scientists extended the life of a mouse by 1 8 per cent(or 4.5 months).Another gene is called IGF-1.Researchers still don’t know how it affects our body.But by reducing its functions the life of...
aAlthough gene technology development can cut a DNA and bring different source genes into another creature. But it can not entirely accurately foresee that whether new protein traits completely accord our requirements or not after having effect. 虽然基因技术开发可能切开脱氧核糖核酸和带领不同的来源基因...