However, it is unknown whether these mice have a normal sleep phenotype. Compared with wild-type control mice, GAD67-GFP knock-in mice had the same amount of non-rapid eye movement (NREM) sleep and rapid-eye movement (REM) sleep, a similar diurnal distribution of sleep, no NREM or REM...
May CA, Nakamura K, Fujiyama F, Yanagawa Y (2008) Quantifi- cation and characterization of GABA-ergic amacrine cells in the retina of GAD67-GFP knock-in mice. Acta Ophthalmol 86:395-400May CA,Nakamura K,Fujiyama F,et al.Quantification and char-acterization of GABA-ergic amacrine cells in...
GAD67-GFP基因敲入小鼠1. Association of 5-HT-like and substance P-like immunoreactive terminals with mesencephalic trigeminal nucleus neurons in the GAD67-GFP knock-in mouse; GAD67-GFP基因敲入小鼠5-羟色胺样和P物质样阳性终末与三叉神经中脑核神经元的联系...
The glutamate decarboxylase 67-green fl uorescent protein (GAD67-GFP) knock-in mouse is a useful model for studying the distribution of GABAergic cells in many tissues and organs. The lungs of these mice contain cells with an intense GFP signal exclusively in the airway epithelium. We aimed ...
(GAD67-GFP) knock-in mouse is a useful model for studying the distribu-tion of GABAergic cells in many tissues and organs. The lungs of these mice contain cells with an intense GFP signal exclusively in the airway epithelium. We aimed to character-ize the GFP-positive cells and to ...
Because the GAD67 protein was absent in the homozygous GAD67-GFP (Δneo) mouse brain (data not shown), we used GAD67-GFP (Δneo) mice as GAD67 KO mice. The GADs DKO mice were obtained by crossing GAD65 KO and GAD67 KO mice. Wild-type mice derived from littermates were collected...
in the brain35and readily influence cellular and vesicular GABA content.36The evidence from knockout mice indicates that GAD67 provides the majority of basal GABA for inhibitory neurotransmission. Deletion of the GAD67 gene in mice results in >90% reduction in basal GABA levels in the brain;37...
Influence of DAXX shRNAi on GAD67mRNA and protein expression. Differentiated HiB5 cells were transduced with lentiviral vectors carrying shRNAi for DAXX. Quantitative RT–PCR was used to measure changes in mRNA expression. Data are expressed as fold change compared with empty vector (tGFP) contr...
Huang J, Wang Y, Wang W, Wei Y, Li Y, Wu S. Preproenkephalin mRNA is expressed in a subpopulation of GABAergic neurons in the spinal dorsal horn of the GAD67-GFP knock-in mouse. Anat Rec 291: 1334-1341, 2008.Huang, J., Wang, Y., Wang, W., Wei, Y., Li, ...
Wang YY, Wei YY, Huang J, Wang W, Tamamaki N, Li YQ, Wu SX (2009) Expression patterns of 5-HT receptor subtypes 1A and 2A on GABAergic neurons within the spinal dorsal horn of GAD67-GFP knock-in mice. J Chem Neuroanat 38(1):75-81...