XY-E30027【中文名称】大鼠磷酸化核因子κB抑制蛋白α(pIKBα)ELISA试剂盒品牌【英文名称】Rat phospho-inhibitory subunit of NF-κBα,pIKBα ELISA试剂盒多少钱 XY-E30028【中文名称】大鼠核因子κB(NF-κB)ELISA试剂盒品牌【英文名称】Rat Nuclear factor-kappa B,NF-κB ELISA试剂盒多少钱 ...
Using luciferase and ChIP assays, we found a potential binding site of nuclear factor kappa-B (NF-魏B) located in the FXR gene promoter which can be bound and activated by NF-魏B. Moreover, hypertonic stress-induced cell death in RMICs was significantly attenuated by FXR activatio...
18.Fiorucci S, Rizzo G, Antonelli E, Renga B, Mencarelli A, Riccardi L, Orlandi S, Pruzanski M, Morelli A, Pellicciari R. A farnesoid x receptor-small heterodimer partner regulatory cascade modulates tissue metalloproteinase inhibitor-1 and matrix metalloprotease expression in hepatic stellate ce...
Loss of hepatic NF- kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation. Proc Natl Acad Sci USA 2006; 103:10544-10551. 74 Bianchi L. Glycogen storage disease I and hepatocellular tu- mours. Eur J Pediatr 1993; 152:S63-S70. Yan-...
[41]. FXR protein is also involved in regulating various molecules such as tumour necrosis factor-α (TNF-α), p21, B-cell CLL/lymphoma 2 (Bcl-2), nuclear factor kappa-B (NF-κB), and other pro-inflammatory cytokines [43]. Thus, the targeted modulation of FXR represents a molecular ...
Excessive bile acid activated NF-kappa B and promoted the development of alcoholic steatohepatitis in farnesoid X receptor deficient mice. Biochimie 2015, 115, 86–92. [CrossRef] [PubMed] 64. Lu, C.; Zhang, F.; Xu, W.; Wu, X.; Lian, N.; Jin, H.; Chen, Q.; Chen, L.; Shao...
Subsequent experiments demonstrated APN's ability to curb the Toll-like receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88)/nuclear factor kappa B (NF-κB) p65 signaling cascade, thereby reducing oxidative damage (malondialdehyde (MDA) and superoxide dismutase (SOD)), microglia-mediated ...
NF-|[kappa]|B and STAT3 |[ndash]| key players in liver inflammation and cancer Cell death and differentiation is a monthly research journal focused on the exciting field of programmed cell death and apoptosis. It provides a single acc... G He,M Karin - 《Cell Research》 被引量: 1269发...
INT-747 enhanced Caco-2 cell viability and inhibited inflammatory response by blocking the NF-[kappa]B pathway after OGD/R injury, which was diminished by a CSE-specific inhibitor (PAG). Thus, we demonstrated that FXR activation enhances intestinal epithelial cell tolerance to I/R by suppressing...
另外SOCS分子还可抑制活化蛋白1(activation protein1,AP1)和核转录因子κB(nuclear factor-kappa B,NF-κB)等促炎信号通路.因此,SOCS分子被认为是一类重要的密切参与调控细胞因子-炎性信号通路的内源性抗炎分子.并有文献报道显示在一些炎症相关疾病中SOCS分子的过表达有助于控制炎症反应.因此,设法上调SOCSs的表达,将...