Their ability to invade body tissues and to produce disease depends on the virulence of the infectious particle, the infecting dose, the route of infection, the resistance or immune status of the host, the organs affected, and the coexistence of infections and other underlying medical conditions....
Fungal infections, also known as mycotic infections, may affect the skin surfaces or the internal organs of the body. The superficial mycotic infections are generally not serious and include such well-known disorders as athlete’s foot (tinea pedis), caused by the dermatophyte Trichophyton. Deep...
[4,5]. SFIs are limited to outer layer of the body and are classified by the infection sites. Some examples in this class are tinea capitis and onychomycosis. Most IFIs are found deep inside of the solid organs and/or bloodstream in immune deficiency populations. Some commonly encountered ...
Fungi generally do not cause invasive infection in healthy individuals. Robust cellular and antibody-mediated immunity and intact mucosal barriers play a major role in shielding the human body from opportunists such as Candida spp., which seek a way of passing through tissues and entering the bloods...
in patients with weakened immune systems.Candidaspecies are the most common cause of fungal sepsis. If one enters the bloodstream or internal organs, it can cause a dangerous and invasive infection thatmay lead to sepsis. The CDC considersCandida auristo be an especially urgent threat because clin...
Their ability to invade body tissues and to produce disease depends on the virulence of the infectious particle, the infecting dose, the route of infection, the resistance or immune status of the host, the organs affected, and the coexistence of infections and other underlying medical conditions....
it spreads to the nervous system and causes swelling around the brain.More than 1 million peoplewith HIV/AIDS worldwide are affected with cryptococcal meningitis each year. The infection often is fatal in those with weakened immune systems, though it’s rare in people who are not ...
Fungal infection Fungal infection Disease caused by fungi or their products. Generalized fungal diseases include allergies to fungal spores or products, poisons or fungal toxins. Narrow fungal diseases only include the disease caused by fungi invading the body. Fungi belong to the plant world, and ...
Fungi are broadly classified in three major groups as follows: Usually, the inhaled aerosolized fungi initiate a primary mycotic infection in the lungs and or paranasal sinuses which is usually self-limiting but may spread to other organs. Frequently, hematogenous dissemination (from lungs, intestine...
Fungal Infection due to Yeasts Fungi produce a spectrum of changes in the lung ranging from benign colonization of airways to malignant angioinvasive infections. Some fungi grow as yeast at body temperatures, whereas others are hyphate molds (Table 9.8). Most fungal yeasts are soil organisms that...