Novel function of IFN-gamma: negative regulation of dendritic cell migration and T cell priming. Wu X,Hou W,Sun S,et al.Novel function of IFN-gamma: negative regulation of dendritic cell migration and T cell priming.J Immunol. 2006... X Wu,W Hou,S Sun,... - 《Journal of Immunology...
Taken together, our data suggest a possible regulatory role of TNF-alpha and IFN-gamma on Fas-mediated apoptosis in the testis through disruption of the balance between different forms of Fas. 展开 关键词: CTLA-4 autoimmune disease regulatory T cell CD25 self-tolerance ...
2003. The role of IFN ␥ nuclear localization sequence in intra- cellular function. J. Cell Sci. 116: 3089 -3098.C. M. I. Ahmed, M. A. Burkhart, M. G. Mujtaba, P. S. Subramaniam, and H. M. Johnson, "The role of IFN𝛾 nuclear localization sequence in intracellular function,...
Inhibition of IκKα/β with a novel selective inhibitor reproduced the impaired monocyte phenotype with decreased production of TNF-α, IL-6, IL-12p70, IL-10, GM-CSF, VEGF, MIP-1β, TNF-β, IFN-α2 and IL-7 in response to an LPS challenge. Surgical patients with infection also ...
(DAMPs)38. TNFα inhibits the proliferation of erythroid precursor cells, and IFNγ-activated macrophages shorten the lifespan of erythrocytes by phagocytosis. IL-6 modulates both the intestinal absorption and the iron release from macrophages through hepcidin, thus leading to hypoferremia and hyper...
Distinct CpG oligonucleotide sequences activate human gamma delta T cells via interferon-alpha/-beta Among several CpG ODN tested, distinct CpG ODN sequences characterized by inducing high amounts of IFN-alpha/-beta in PBMC elicited strong gamma delta T... S Rothenfusser,V Hornung,A Krug,.....
Despite this, both the Th1 cell–associated cytokine IFN-γ and airway neutrophilia have been implica... Mang,Yu,Eckart,... - 《Journal of Clinical Investigation》 被引量: 114发表: 2011年 Intracellular degradation of Fc gamma RIII in mouse bone marrow culture-derived progenitor mast cells ...
V. Correlation of reaginic activity wth gamma-E-globulin antibody. J. Immunol. 97, 840–853 (1966). CAS PubMed Google Scholar Selye, H. The Mast Cells xxix, 498 p. ( Butterworths, Washington, 1965 ). Google Scholar Bloom, G.D. Structural and biochemical characteristics of mast cells...
YTHDF1 depletion increases the secretion of IFN-γ and overexpression of IFN-γ receptor 1 and promotes the expression of MHC-I, which realizes the self-antigen presentation by immunogenic tumor cells [104] (Table 2). Table 2. Regulation of methylation modifications in the immune microenvironment...
Three major groups of ILCs have been defined on the basis of similarity in their production of signature cytokines, developmental requirements, and phenotypic markers. Group 1 ILCs produce IFN-γ, express the T-box transcription factors (TF) T-bet and/or Eomesodermin (Eomes), group 2 ILCs ...