participants of this study were recruited as part of previous and ongoing IRB-approved studies. Out of a total of 5619 bladder isolates in our urinary bacteria collection, we selected 1050 strains for whole-genome sequencing. Some isolates came from the same participant...
It is well-established that parental obesity is a strong risk factor for offspring obesity. Further, a converging body of evidence now suggests that maternal weight profiles may affect the developing offspring’s brain in a manner that confers future obe
There are no published longitudinal studies from Africa of people with dementia seen in memory clinics. The aim of this study was to determine the proportions of the different dementia subtypes, rates of cognitive decline, and predictors of survival in p
Oral squamous cell carcinoma in minors is considered to be a distinct entity from OSCC in older patients, with an uncertain etiology. Human papillomavirus (HPV) infection may trigger the initiation and promote the progression of OSCC, but these roles have not been firmly established.We aimed to ...
found that among very old people with Mini-Mental State Examination (MMSE) scores ≥ 10, the GDS-15 was useful for assessing depressive symptoms [6]. A meta-analysis found evidence that the scale's factor structure varies depending on linguistic and cultural factors, and the number of ...
Overactive bladder (OAB) presents a high prevalence of 16–18% worldwide. The pathophysiology of OAB is still poorly understood while effective therapy or countermeasure are very limited. On the other hand, medicinal plants and herbal remedies have been
See full prescribing information for a list of interacting drugs. (7.1) (7) Tizanidine (CYP1A2) Substrate:Potential for substantial increases in blood concentrations of tizanidine resulting in hypotension, bradycardia or excessive drowsiness; avoid concomitant use, if possible. (7.2) (7) ...
The management of adults with signs and symptoms of primary or secondary gout (acute attacks, tophi, joint destruction, uric acid lithiasis, and/or nephropathy) • The management of adult and pediatric patients with leukemia, lymphoma and solid tumor malignancies who are receiving cancer therapy ...
However, suicidal thoughts and depressive symptoms can also increase risk of substance use as one study showed that many youth acknowledged that problem substance use was a slow and passive form of suicide in which they gave up on life [16]. History of depression is a consistent predictor of ...
Therefore, we did not exclude participants with corresponding symptoms. The decision to use the age of participants starting at 55 was supported by the evidence that much of the cognitive decline observed in old adults already starts at middle age [49], so we expected that individuals from this...