Cell composition deconvolution (CCD) is a type of bioinformatic task to estimate the cell fractions from bulk gene expression profiles, such as RNA-seq. Many CCD models were developed to perform linear regression analysis using reference gene expression
Genomic Profiles of Drug Sensitivity (GPDS) ranked lists were built by computing the Pearson correlation coefficient (PCC) between the expression of each gene and the potency of a drug across the cell lines for which drug potency was measured. At the end of this process, each GPDS is a rank...
Salmonella enterica serovar Hadar (S. Hadar) is a highly prevalent foodborne pathogen and therefore a major cause of human gastroenteritis worldwide. Outer membrane proteins whose production is often regulated by environmental conditions also play import
The classical ethanologenic cassette for microbial heterologous expression is composed of pyruvate decarboxylase (pdc) and alcohol dehydrogenase II (adh) from microorganisms, such asZymomonas mobilis(Fig.1, highlighted in red; [15]). This pathway requires the cell to supply adequate quantities of the...
Bioethanol can be produced by introducing pyruvate decarboxylase (PDC) and alcohol dehydrogenase (ADH) genes fromZ. mobilisinto the shuttle vector and then transformSynechosystissp. [127,128] (Table1). Table 1Biofuel and biochemical production by cyanobacteria ...
Ever since the recent completion of the peach genome, the focus of genetic research in this area has turned to the identification of genes related to important traits, such as fruit aroma volatiles. Of the over 100 volatile compounds described in peach,
Cyanobacteria are photosynthetic prokaryotes that thrive in a wide variety of habitats. Their occurrence in aquatic environments is of particular interest due to their ability to form dense and potentially toxic blooms under certain environmental conditions [1, 2]. Some of the toxins produced include ...
By expressing a bacterial pyruvate decarboxylase (pdc) and alcohol dehydrogenase (adh) from the bacterium Z. mobilis in the cyanobacterium Synechococcus sp. PCC 7942, Deng and Coleman (1999) obtained a recombinant microorganism which can produce up to 230 mg/L ethanol directly from CO2 within 4 ...
By expressing a bacterial pyruvate decarboxylase (pdc) and alcohol dehydrogenase (adh) from the bacterium Z. mobilis in the cyanobacterium Synechococcus sp. PCC 7942, Deng and Coleman (1999) obtained a recombinant microorganism which can produce up to 230 mg/L ethanol directly from CO2 within 4 ...
[90]. By introducing thecfagene fromE. coliinto cyanobacteriumSynechocystissp. PCC 6803, CFAs were produced in engineered cells with up to 30% of total fatty acids [90]. In addition, engineering their biosynthesis could improve the tolerance of bacterial host to harsh conditions. For example, ...