There is also several evidence that suggest that AMA-1 forms a complex with RON2 to form the moving junction during invasion of merozoites into erythrocytes [17,18,19,20,21,22,23]. According to a previous report, AMA-1 can induce a protective immune response that produces antibodies that ...
An O-shaped patch (Cutimed Hydro L, BSN medical GmbH, Hamburg, Germany) with an outer diameter of 3.1 and an inner diameter of 1.8 cm was bonded onto the FTSE surface to form round application sites (2.54 cm2) and prevent cross-contamination of the culture medium (Air Liquid Interface ...
The latter impairment is the most serious form of DNA damage [135]. A disfigured genome is the stimulus that initiates DNA damage response (DDR) processes [136,137]. These consist of a series of complex events that heal the DNA lesions. When the damage is highly deleterious, however, it ...
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Expanded tandem repeat-containing RNA (xtrRNA) may not be transcribed due to epigenetic silencing, thereby causing loss of gene function. If transcribed, xtrRNA may become trapped in the cell nucleus where it can form focal aggregates and functionally deplete important RNA binding proteins. The ...
Studies of complex formation using a longer, dimeric myosin-IIA construct demonstrated that S100A4 binding dissociates the two myosin-IIA polypeptide chains to form a complex composed of one S100A4 dimer and a single myosin-IIA polypeptide chain. This interaction is mediated, in part, by the ...
No-go Decay (NGD) also acts to release ribosomes that are stalled on the mRNA [6]. The onset of NGD in yeast involves the proteins Hbs1p, a eukaryote-specific paralogue of eEF1A and eRF3 in the EF1 family [15, 16] and Dom34p (synonym Pelota), a paralogue of eRF1 [29, 30]....
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Given this data and the fact that PWM models are used for three decades in practically unchanged form, attests to their tremendous applicability. However, in order to use such a model to determine potential binding sites of a TF with a known motif, one needs to choose a log-odds threshold...
PSC is a serious disorder with yet unknown etiology; however, a role has been proposed for immune dysregulation in the progression of PSC.4Bacterial infections secondary to bile fluid stasis may also complicate PSC.7On the other hand, the most common form of secondary cholangitis is acute cholan...