First introduced by Dixon et al. in 2012, ferroptosis is a form of programmed cell death (PCD), a term distinct from other modes of cell death such as necrosis, apoptosis, autophagy, necroptosis, and pyroptosis, which is essential for maintaining homeostatic balance [7,8,9]. Morphologically,...
i Electron microscopy image of the form of mitochondria in neutrophils. j Intracellular iron colorimetric assay showing the concentration of total Fe in neutrophils. k LPO assay showing the concentration of LPO in neutrophils from bone marrow. l Immunostaining of MBP (green) and nuclei (DAPI, ...
Ferroptosis is a newly recognized form of regulatory cell death characterized by severe lipid peroxidation triggered by iron overload and the production of reactive oxygen species (ROS). However, the role of ferroptosis in severe acute pancreatitis(SAP) has not been fully elucidated. Methods We esta...
Additionally, they identified a compound termed ferrostatin-1 (Fer-1) that obviously inhibits cell death caused by RSL3 by scavenging lipid ROS while not affecting other types of cell death and officially termed this iron-dependent form of cell death as ferroptosis [1]. Subsequently, the study ...
Notably, as a novel form of regulated cell death [10], ferroptosis has been reported to be involved in osteoporosis [11, 12]. Ferroptosis is featured as iron overload and the accumulation of iron-dependent lipid peroxidation. Intracellular iron overload can produce excess amounts of reactive ...
Ferroptosis is a form of cell programmed death that is regulated by ferredoxin-dependent iron metabolism and is triggered by the toxicity of lipid peroxidation products on the cell membrane [9]. Research has shown that this unique cell death mechanism is driven by phospholipid peroxidation dependent...
dahliae in crude samples from naturally infected trees with very low infection levels, while nested PCR and SYBR qPCR failed to detect the pathogen in an unpurified form. Conclusions This study describes the development of a new real time LAMP assay, targeting the ITS region of the rRNA gene ...
You can create full text search queries anyplace in SilverStream that you can put a WHERE clause. This includes forms, views, pages, business object, and data-loaded form controls. You can create full text search queries one of two ways: ...
Ferroptosis is a form of cell death caused by iron-dependent lipid peroxidation and ROS accumulation characterized by the reduction or loss of mitochondrial cristae and rupture of the outer mitochondrial and mitochondrial membranes condensation [72]. Zhang et al. [73] found that transferrin ...
DLP4710 is part of the chipset comprising of the DLP4710 DMD, DLPC3439 display controller and DLPA3000/DLPA3005 PMIC/LED drivers. The compact physical size of the DLP4710 coupled with the controller and the PMIC/LED driver provides a complete system solution that enables small form factor, ...