Perinatology.comoffers a free online allele frequency calculator. This calculator uses the Hardy-Weinberg equation to estimate the frequency of the carrier state (2pq) for an autosomal recessive trait. All you have to do is add the population that has recessive traits either in percentage or in ...
In population genetics, allele frequency is used to reflect the genetic diversity of a population species. It is also referred to as gene frequency. It is a measure of relative frequency of a gene on a genetic locus in a population. The frequency is expressed in terms of percentage. Hardy-...
To improve the clinical utility of NGS in NSHL, one useful approach is to consider the allele frequency (AF) of a gene variant. Large reference datasets such as Exome Aggregation Consortium (ExAC) and Genome Aggregation Database (gnomAD) not only provide high-resolution variant frequencies, but...
Power was computed using TDT Power Calculator [15] varying SNP minor allele frequency (MAF) and genetic relative risk (GRR).doi:10.1371/journal.pone.0104212.t004E. K. AllenA. ManichaikulWei-Min ChenS. RichK. DalyM. SalePLOS ONE
An extension of the ABO system to include an arbitrary number of codominant alleles has been made, and such a multiple allele locus has been called the ABO-like system (Yasuda and Kimura, 1968). Obviously, one of the most important examples in this genetic system is the HLA polymorphisms. ...
The allele frequency calculator checks how often a gene occurs in the population, based on the prevalence of the disease it causes, using the Hardy-Weinberg equation.
Fisher's exact test of 2 × 2 contingency tables was used to calculate the two-tailed p values associated with allele frequencies in case and control groups. Fisher's exact test was performed using the GraphPad QuickCalcs Online Calculator for Scientistshttp://www.graphpad.com/quickcalcs/index.cf...
3allele in a White American population. The aim of the present study is to determine the presence and frequency ofCYP2C9pVNTRin a Spanish population, as well as analyzing whether thepVNTR-Sallele is in LD with theCYP2C9*3allele in this population. Subjects and Methods: A total of 209...