【关键词】 胃肿瘤·药物疗法 联合·治疗结果 【ABSTRACT】 Objective: To investigate the therapeutic effect and side effects of FOLFOX4 and XELOX as neoadjuvant chemotherapy on locally advanced gastric cancer. Methods: Sixty-eight patients with locally advanced gastric cancer were randomly assigned into ...
chemotherapy after operation and 81patients received FOLFOX chemotherapy.The disease-free survival,5-year survival rate,adverse reaction occurrence and quality of lifewere compared between the two groups.Results In the XELOX group,34 patients (37.78%)developed disease progression,and 28patients (34.57%)...
13. Bruheim K, Guren MG, Skovlund E, et al: Late side effects and quality of life after radiotherapy for rectal cancer. Int J Radiat Oncol Biol Phys 76:1005-1011,2010 14. Jalil O, Claydon L, Arulampalam T: Review of neoadjuvant chemotherapy alone in locally advanced rectal cancer. J ...
[Methods]A total of 90 patients with advanced colorectal cancer were equally divided into the control group and the observation group,with 45 cases in each.Both groups were treated with FOLFOX chemotherapy;however,the observation group was additionally treated with bevacizumab.The therapeutic effect ...
时辰组和常规组的PFS分别为6.3个月和6.0个月,差异无统计学意义(P=0.476),0S分别为17.8个月和15.9个月,差异有统计学意义(P二0.003)o两方案常见的毒副反应为恶心呕吐、中性粒细胞减少、脱发和疲乏,毒副反应在时辰组中的发生率低于常规组(P0.05)・ThePFSinchronochemotherapygroupandroutinechemotherapygroupwere6.3...
5、 in routine chemotherapy group ( p key words advanced colorectal cancer; chronochemotherapy; oxaliplatin;fluorouracil; toxicity目前,结直肠癌的发病率日趋见涨,严重危害人类健康。近年来,由于新药的应用和治疗策略的改变大大提高了晚期 结直肠癌患者(acc)的生存期。f0lf0x6方案目是前公认的 acc 一线治疗的标...
广州医学院 硕士学位论文 FOLFOX、FOLFIRI方案在进展期直肠癌新辅 助化疗中的应用研究 研究生：宋靖方 导师：雷建教授 申请学位级别：医学硕士年级：2009级 学科专业：普通外科学研究方向：胃肠疾病 论文提交日期：2012年5月论文答辩日期：2012年5月 学位类型：医学专业学位学位授予单位：广州医学院 2012年5月 ...
13. Bruheim K, Guren MG, Skovlund E, et al: Late side effects and quality of life after radiotherapy for rectal cancer. Int J Radiat Oncol Biol Phys 76:1005-1011,2010 14. Jalil O, Claydon L, Arulampalam T: Revie...
4 1 cases in each group. Group A was treated with SOX chemotherapy scheme,and group B was treated with modified folfox6 chemotherapy scheme.The short-term e f i cacy,quality of life,side effects,median disease progression and survival time were compared between the two groups. Results In ...
FOLFOX regime (P=0.038).The major treatment-related side effects included leucopenia, neutropenia, nausea, vomiting, fatigue, erythra and etc, mainly in grade1-2.The median OS of patients receiving chemotherapy was 26.9 months, superior to 4.4 months of patients receiving non-chemotherapy (P<...