FOLFIRINOX an option in colorectal cancer with liver metastasesColorectal-cancer, treatmentFluorouracil, therapeutic useFolinic-acid, therapeutic useIrinotecan, therapeutic useOxaliplatin, therapeutic useInpharma Weekly -doi:10.2165/00128413-200816490-00051None...
We evaluated the efficacy and safety of cetuximab plus 5-fluorouracil, leucovorin, irinotecan, and oxaliplatin (FOLFIRINOX), the ERBIRINOX regimen, as first-line treatment in patients with unresectable metastatic colorectal cancer (mCRC). PATIENTS AND METHODS: In a phase II study, treatment ...
[2]Datta, J., et al., Role of Hepatic Artery Infusion Chemotherapy in Treatment of Initially Unresectable Colorectal Liver Metastases: A Review. JAMA Surg, 2019. [3]Ueno, M., et al., Nivolumab alone or in combinat...
Personalized medicine is a crucial concept in the current treatment paradigm for metastatic colorectal cancer, and its extension to the management of non-metastatic colorectal cancer, particularly high-risk stage III CC, which carries high potential of progression to metastatic disease, is warranted. Th...
[11] SCLAFANI F, BROWN G, CUNNINGHAM D, et al. Systemic chemotherapy as salvage treatment for locally advanced rectal cancer patients who fail to respond to standard neoadjuvant chemoradiotherapy[J]. Oncologist, 2017, 22(...
doi:10.1001/jamanetworkopen.2023.50756 Key Points Question Does fluorouracil, leucovorin, liposomal irinotecan and oxaliplatin (NALIFIROX) confer a survival benefit as first-line treatment for patients with metastatic pancreatic cancer compared with fluorouracil, leucovorin, irinotecan, and oxaliplatin (...
prospective data to inform the most adequate management of small bowel adenocarcinoma is lacking and most treatment recommendations are being based on expert agreement and relying on extrapolated data from colon cancer.4 This is despite the fact that genomic profiling suggests that small bowel adenocarci...
FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis. Lancet Oncol. 2016;17(6):801-810.PubMedGoogle ScholarCrossref 14. Katz MH, Shi Q, Ahmad SA, et al. Preoperative modified FOLFIRINOX treatment followed by capecitabine-based chemoradiation for ...
Dosage iterations of modified FOLFOX-4, FOLFOX-5, and FOLFOX-7 have been used to treat pancreatic, colorectal, and bladder cancers11,12,13. Cold atmospheric plasma (CAP) has been extensively studied in various biomedical fields. It is a novel approach to targeted cancer treatment and has ...
Background Gemcitabine plus cisplatin is regarded as the standard first-line therapy for patients with advanced biliary tract cancer (BTC); however, no standard chemotherapy has yet been recommended after treatment failure. Modified FOLFIRINOX (mFOLFIRINOX) appears to be a better-tolerated regimen, whi...