Serum phosphate, calcium, and intact PTH could be regulators of FGF-23 levels in uremic patients on maintenance hemodialysis. Our results may provide new insights into the pathophysiologic effects of FGF-23 on calcium-phosphate homeostasis.Kidney InternationalImanishi,...
After 28 days, TmP/GFR was lowered from 1.10 mmol/L to 0.48 mmol/L; this was accompanied by increases in NcAMP, ionized calcium, and bone turnover markers. In conclusion, the effect of FGF23 excess on TmP/GFR is altered by PTH such that the effect is ameliorated by hypoparathyroidism ...
G. et al. Effects of dietary phosphate and calcium intake on fibroblast growth factor-23. Clin. J. Am. Soc. Nephrology: CJASN. 6, 383–389. https://doi.org/10.2215/CJN.04730510 (2011). Article CAS Google Scholar Ito, N. et al. Effect of acute changes of serum phosphate on ...
Because this change occurred after the recovery of both serum 1,25(OH)2D and calcium, the suppression of PTH is likely because of the effect of the elevations of 1,25(OH)2D and calcium. Download: Download full-size image Figure 4. Effects of anti-FGF23 antibodies on calcium and PTH ...
随着参与国和组织活动逐年稳定地增长,世界骨质疏松日的影响日益扩大,到了1998年世界卫生组织(WHO)开始参与并作为联合主办人,担当了一个非常重要的角色,并将世界骨质疏松日改定为每年10月20日。为迎接2022骨质疏松日,陆续更新公众号内部...
fgfrs细胞分化klothohspgshbgm 硕士学位论文 FGF23/FGFRs调节成骨细胞分化的作用和机制研究 莫奇非 指导教师陈林教授 导师组成员苏楠副教授 培养单位 陆军军医大学陆军特色医学中心 战伤组织修复与康复医学研究室 申请学位类别硕士学术学位专业名称外科学(野战外) 答辩委员会主席罗凌飞教授 答辩委员周元国、谭颖徽、李礼、...
Serum phosphate (iP), calcium, Heart and Vessels (2021) 36:414–423 415 and intact parathyroid hormone (iPTH) are proposed to regulate FGF23 levels in uremic patients on maintenance hemodialysis [6], and current data suggest higher circulat- ing levels of FGF23 are associated with mortality ...
It appears that FGF23 can unfold its most potent pathologic actions on the heart in the context of CKD (Figure 1b). Although the precise nature of CKD-associated factors and the crosstalk among them and with FGF23 remain elusive, one could envision a synergistic effect between high serum lev...
Our objective was to quantitatively estimate the blood FGF23 level in birds, and to examine its relationship to diet and blood levels of other components of phosphate and calcium homeostasis. Methods: A systematic search of Agricola, Embase and Medline identified 86 studies focused on FGF23 in ...
Effect of hydrolysis-resistant FGF23-R179Q on dietary phosphate regulation of the renal type-II Na/Pi transporter. Pflugers Arch. 2003;446:585-592. 42 Segawa H, Yamanaka S, Ohno Y, Onitsuka A, Shiozawa K, Aranami F, Furutani J, Tomoe Y, Ito M, Kuwahata M, Imura A, Nabeshima Y,...