Fatty acid oxidationFatty liverMitochondriaRespiratory chainSteatosisDrug-induced inhibition of mitochondrial fatty acid 尾-oxidation (mtFAO) is a key mechanism whereby drugs can induce steatosis. The type and severity of this liver lesion is dependent on the residual mtFAO flux. Indeed, a severe ...
The mitochondrial fatty acid 尾-oxidation is integral to normal cellular metabolism and maintenance of cellular energy supplies. Disorders of this pathway interrupt the body's ability to deal with fasting states, as well as compromising the functioning of organs and systems whose high-energy ...
Immunohistochemical Localization of Mitochondrial Fatty Acid 尾-Oxidation Enzymes in Rat TestisMotoaki FukasawaKimie AtsuzawaKenmei MizutaniAyami NakazawaNobuteru UsudaFukasawa M,Atsuzawa K,Mizutani K,et al.Immunohistochemi-cal localization of mitochondrial fatty acidβ-oxidation enzymes in rattestis.Journal ...
Role of fatty acid uptake and fatty acid beta-oxidation in mediating insulin resistance in heart and skeletal muscle. Biochim Biophys Acta 2010;1801:1-22.Zhang L, Keung W, Samokhvalov V, Wang W, Lopaschuk GD. Role of fatty acid uptake and fatty acid beta-o...
Loss of Igκ led to a decrease in the expression of mitochondrial respiratory chain complexes III and IV, resulting in aberrant fatty acid β-oxidation (FAO) and lipid accumulation, which in turn inhibited HCC cell proliferation and...
These metabolic changes are also seen as secondary abnormalities in dysfunction of fatty acid 尾-oxidation, and have also been reported in autism. It is ... Tonya,Clark-Taylor,and,... - 《Medical Hypotheses》 被引量: 97发表: 2004年 Impaired fatty acid oxidation in children on valproic acid...
To inhibit 尾-catenin by ICG-001, an inhibitor of 尾-catenin, could significantly block CXCR4-suppressed fatty acid oxidation. Taken together, our results indicate that CXCR4 is a key mediator in tubular cell senescence and renal fibrosis. CXCR4 promotes tubular cell senescence and renal ...
Schulz (1985) 3-Hydroxyacyl-CoA epimerase is a peroxisomal enzyme and therefore not involved in mitochondrial fatty acid oxidation. FEBS Left., 185: 129-134.Chu, C-H. amp; Schulz, H. (1985) FEBS Lett. 185, 129–134Chu, C-h., and H. Schulz. 1985. 3-Hydroxyacyl-CoA epimerase is a...
Mitochondria are involved in fatty acid 尾-oxidation, the tricarboxylic acid cycle, and oxidative phosphorylation, which provide most of the cell energy. M... D Pessayre,A Mansouri,D Haouzi,... - 《Cell Biology & Toxicology》 被引量: 681发表: 1999年 Fatty acid cycling mechanism and mitocho...
Estimations of the amount of ATP produced by both glycolysis and by fatty-acid 尾-oxidation indicated that the 2 activities were essentially equal, which is in contrast to that reported for the epidermis. The results suggest that the oral mucosal epithelium, like the epidermis, is an active ...