This title on Huntington's disease, written for sufferers and their families, offers advice on living with this disabling illness. Written as much for carers as for the patients themselves, the book aims to answer questions that both sufferer and carer might have. It clearly explains the role...
Unmet needs for healthcare and social support services in patients with Huntington's disease: a cross-sectional population-based study In order to plan and improve provision of comprehensive care in Huntington's disease (HD), it is critical to understand the gaps in healthcare and social s......
As said earlier, heredity is the prime and probably the only reason behind the appearance of this condition. When a defective gene is passed on from the parent to a child, it may result in Huntingtons disease. A trait in a person is determined by two chromosomes, one from the father an...
However, the availability of several transgenic or knock-in animal models, the rising clinical knowledge about the biology and phenotype of the disease in both manifest and pre-diagnosed stages through large observational and biomarker studies, and the progress in drug development and validation ...
colon; The accuracy of the knowledge of genetic patterns of Huntington's disease was studied by interview in 14 patients who had been in regular contact with physicians. Only one patient had completely accurate knowledge of the genetic risk entailed by autosomal dominance. Inaccurate know...
byHuntington disease, a hereditary neurological disorder about which little was known at the time and which would later afflict Guthrie too. The family lived near the relocatedCreeknation in Okemah,Oklahoma, a small agricultural andrailroadtown that boomed in the 1920s whenoilwas discovered in the...
Huntington's disease is a neurodegenerative condition, characterized by movement disorders, cognitive decline, and psychiatric disturbance. We review the pharmacological management of the various movement disorders associated with the disease, the cognitive decline and the commonly encountered behavioral ...
Although respondents who were aware that they carried the Huntington's disease mutation reported the highest levels of discrimination, participation in genetic testing was not associated with increased levels of genetic discrimination. Family history of Huntington's disease, rather than the result of ...
In the nuclear fuel reprocessing plant, dissolver off-gas (DOG) is supposed to include nitrogen oxides (NOX) during the operation. An adsorption process by mineral zeolite has been studied for DOG treatment that follows a dehydration and iodine removal process. According to the results, the ...
The family of histone deacetylases (HDACs) has recently emerged as important drug targets for treatment of slow progressive neurodegenerative disorders, including Huntington's disease (HD). Broad pharmaceutical inhibition of HDACs has shown neuroprotective effects in various...