Brain-selective estrogen treatment in symptomatic 3K mice significantly increased the tetramer-to-monomer ratio, turnover by autophagy of aggregate-prone monomers, and neurite complexity of surviving DAergic and cortical neurons, in parallel with benefits in motor performance. Our findings support an ...
ContextDespite decades of accumulated observational evidence, the balance of risks and benefits for hormone use in healthy postmenopausal women
Seeking to better understand the key role the female hormone estrogen plays in maintaining energy balance and weight control, a group led by researchers at Baylor College of Medicine looked into estrogen interactions with specific brain regions that provide these anti-obesity benefits. The team reveals...
Pregnancy has its skin benefits due to the high levels of estrogen and progesterone which tend to protect the skin from blemishes. In fact, some acne will improve or disappear entirely during pregnancy replaced by the healthy “glow” of pregnancy, only to resurface once the baby has been deli...
Learn More About the Benefits of DIM DIM may be one of the easiest and best ways to promote healthy estrogen balance. DIM, which stands for diindolylmethane, comes from the plant chemical I3C, short for indole-3-carbinol.DIM stimulates the body to metabolize bad estrogens, not your good one...
(ER)α expression in vitro, and the metabolic benefits of this treatment for mice on a high-fat diet are lost in mice that do not express ERα in all tissues45. It has been assumed that at least a part of the metabolic and anti-aging benefits of this treatment are centrally mediated ...
No research has been performed on other benefits or risks. Supplemental Progesterone Progesterone should be used as adjunct treatment with estrogen whenever a woman has a uterus to protect against endometrial pathology. It is not necessary when a woman has had a hysterectomy since progesterone does ...
The WHI trials appeared to support the “timing hypothesis,” that cardiovascular benefits may occur when therapy is initiated near to the time of menopause. However, initiating hormone treatment after 10 or more years of estrogen deficiency may increase risk for cardiovascular events. The loss o...
In recent years, hormone replacement therapy (HRT) or estrogen combined with exercise have been proposed as potentially therapeutic agents for postmenopausal women, as these agents may potentially limit muscle damage and inflammation and stimulate repair in this population. While the benefits and ...
“Ovarian conservation until age 65 benefits long-term survival…. There is sustained, but decreasing, benefit until the age of 75, when excess mortality for oophorectomy is less than 1%.” 2007 –Ovarian conservation at the time of hysterectomy for benign disease ...