大肠杆菌(Escherichia coli),在1885年发现的,在相当长的一段时间内,一直被当作正常肠道菌群的组成部分,认为是非致病菌。直到20世纪中叶,才认识到一些特殊血清型的大肠杆菌对人和动物有病原性,尤其对婴儿和幼畜(禽),常引起严重腹泻和败血症。大肠杆菌又是如何产生的呢?又当如何消灭呢?L就爱涨知识的秒拍视频 ...
coli) in combination with anti-PD-1 antibodies to treat GBM, with the aim of exploring the immune-activating potential of E. coli in GBM and its synergistic effect on anti-PD-1 therapy. Methods The E. coli and anti-PD-1 antibody therapy were administered intravenously and intraperitoneally,...
coli) in combination with anti-PD-1 antibodies to treat GBM, with the aim of exploring the immune-activating potential of E. coli in GBM and its synergistic effect on anti-PD-1 therapy. Methods The E. coli and anti-PD-1 antibody therapy were administered intravenously and intraperitoneally,...
Potential O-acetylation of the sialic acid residues of Escherichia coli K1, groups W-135, Y, and C meningococci, and group B Streptococcus capsular polysaccharides modifies their immunogenicity and susceptibility to glycosidases. Despite the biological importance of O-acetylation, no sialic or polysia...
We did this study to investigate the prevalence of the mcr-1 gene in clinical isolates from patients with bloodstream infections in China. Clinical isolates of Escherichia coli and Klebsiella pneumoniae were collected from patients with bloodstream infections at 28 hospitals in China, then screened ...
Glycerol dehydratase (gdrAB-dhaB123) operon from Klebsiella pneumoniae and NADPH-dependent 1,3-propanediol oxidoreductase (yqhD) from Escherichia coli were
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大肠杆菌(Escherichia coli,E. coli)在生物制药工业中生产重组蛋白方面发挥了重要作用,它是第一个用于生产生物药物的表达载体,其发展促使了1982年首个生物技术产品Humulin®(用于治疗糖尿病的人胰岛素)的诞生。E.coli具有生长快速、基因操作方便、重组蛋白合成速度快等优点,也存在一些固有障碍,如密码子使用偏好、缺乏翻...
ArcA is a global regulator that switches on the expression of fermentation genes and represses the aerobic pathways when Escherichia coli enters low oxygen growth conditions. The metabolic profile of E. coli CT1062 (ΔarcA)and CT1061 (arcA2) grown in microaerobiosis with glycerol as carbon...
and Park, J.H., Integration of systems biology with bioprocess engineering: L-threonine production by systems metabolic engineering of Escherichia coli, Adv... YL Sang,HP Jin - 《Advances in Biochemical Engineering/biotechnology》 被引量: 33发表: 2010年 Integration of systems biology with bioproces...