Sputum inflammatory cell abundance was assessed in 37 samples by microscopy using cytospin (16 samples had insufficient cell count for cytospin analysis). Overall, sputum inflammatory cell abundances were similar between mepolizumab and placebo groups as measured by cytospin, though mepolizumab-treated part...
Underestimation is slight and usually clinically insignificant, but occasionally eosinophils are completely misclassified. Using the Sysmex analyzer, a GE gate can be designed to normalize the eosinophil count.doi:10.1111/j.1939-165X.2011.00357.x...