doi:10.1016/j.brainres.2009.05.039ApoptosisAutophagyDopamine neuronsHuntington's diseasePark-2 geneUbiquitin proteosomal systemHuntington's disease (HD) is a neurodegenerative disorder caused by an expansion of polyglutamines which makes huntingtin more resistant to degradation. Parkin is an ubiquitin ...
However, the molecular mechanisms underlying the pleiotropic and heterogenic roles of the 19q13.32 region in human aging and disease remain elusive. Regulation of the expression levels of the genes encoded by this region may contribute to its pleiotropic effects. It has been shown that APOE-...
Rustad L, Campbell J, Dukes JS, Huntington T, Fallon Lambert K, Mohan J, Rodenhouse N (2012) Changing climate, changing forests: the impacts of climate change on forests of the northeastern United States and eastern Canada. US FOREST SERVICE 11 CAMPUS BLVD SUITE 200 NEWTOWN SQUARE PA 19073...
Huntington DiseaseParkinson DiseaseBiogenic AminesMonkeys with lesions in the ventromedial area of the brain stem exhibit neurological and neurochemical deficits which are similar to those observed in Parkinson's syndrome. This report will review some studies on the disposition, biosynthesis and metabolism ...