It is not clear,,however, whether estrogens have a major role in whole body anabolism in males. We investigated the metabolic effects of selective estrogen suppression in the male using a potent aromatase inhibitor, Arimidex (Anastrozole). First, a dose-response study of 12 males (mean age, ...
A notable change that occurs in estrogen signaling over human aging is the menopause transition, which is driven by changes in the follicular reserve of the ovaries. Ovarian aging is principally classified by a decline in both the quantity and the quality of oocytes, with primordial follicles grad...
In some animals, levels of oxytocin receptors have been correlated with concentrations of circulating steroid hormones (namely, estrogen and progesterone). Although there has been speculation about the significance of similar associations in humans, whether such associations exist in the first place is ...
and antioxidant defenses, has been identified to play a key role in the pathogenesis of subfertility in both males and females. The adverse effects of OS on sperm quality and functions have been well documented. In females, on the other hand, ...
As a result, Lupron Depot stops testosterone production by the testes in males. In females, it causes the ovaries to stop making estrogen and progesterone. Once treatment is stopped, hormone levels typically return to normal.Lupron Depot first gained FDA approval on April 9, 1985. There is ...
Elevation of VTG in males is a well-known marker of estrogen exposure in fish and amphibians (see below), and it has been pre- sumed that the same applies to mollusks, although this has been challenged (Scott 2012, 2013). VTG-like protein (ALP) in females was also apparently increased ...
Biological effects of bisphenol A Although in the latter part of the 20th century BPA found its widest use in plastics, in the 1930s scientists had developed it as a synthetic estrogen and noted the possibility of carcinogenic (cancer-causing) properties. The significance of its estrogenic behavio...
Estrogen therapy, thiazide diuretics and beta-blockers, are sometimes associated with massive rises in plasma triglycerides, especially in subjects with familial hypertriglyceridemia. In such cases, discontinuation of the specific etiologic agent may obviate the need for specific drug therapy of ...
In females, ID-induced changes indicated enhanced activity of oxidative phosphorylation and fatty acid metabolism, which were contrary to the ID effects in males. Prenatal choline supplementation induced the most robust changes in gene expression, particularly in iron-deficient animals where it partially...
They are naturally found in many plant foods. The chemical structure of PE is diverse and includes flavonoids, isoflavonoids, lignans, coumestans, and stilbenes, which modulate estrogen receptor (ER) signaling pathways as well as estrogen functions and metabolism; thus, PEs are also considered ...