As one of the first early symptoms of Parkinson’s disease, tremor usually affects only one side of the body first, then spreads to affect both sides as the disease progresses.The main type of tremor seen in people with Parkinson’s is known as a resting tremor. In this type of tremor,...
Parkinson's disease (PD) occurs due to lack of dopamine-producing ("dopaminergic") neurons predominately in the particular region of substantia nigra (SN) in the brain, with manifestations of muscle rigidity, changes in gait movement, tremors and speech. Parkinsonism potentially causes speech ...
Psychiatric complaints are common in Parkinson's disease (PD), and have a significant influence in disease outcome and quality of life. Little attention has been paid to psychiatric symptoms at early stage disease. We aimed to screen a population of early stage PD patients for psychiatric symptoms...
PARKINSON’S DISEASE is a progressive disorder caused by the deaths of neurons(神经元) in parts of the brain. Symptoms include loss of motor control, mood disturbance and ruined sleep. Although it is incurable,early medical treatment can, however, relieve these symptoms and lengthen survival. ...
While movement problems are the main symptom of Parkinson's disease, a new study shows that even early in the course of disease people frequently experience many non-motor symptoms such as drooling, anxiety and constipation. The study is published in the
Joanne P. RobinsonSchool of NursingRutgers UniversityCamdenNew JerseyChristine W. BradwaySchool of NursingUniversity of PennsylvaniaPhiladelphiaPennsylvaniaLisette Bunting‐PerrySchool of NursingUniversity of DelawareNewarkDelawareHelene MoriartyM. Louise Fitzpatrick College of NursingVillanova UniversityVillanova...
Apathy is a frequent and disabling behavioral disorder in patients with Parkinson's disease (PD). Its prevalence in treatment-naive patients with early-stage PD has not been extensively investigated. Moreover, whether apathy is related to other non-motor symptoms in early-stage PD is unknown. Ou...
Adherence to dietary patterns that emphasize vegetables, fruits, nuts, and grains, such as in the Mediterranean diet, is inversely associated with prodromal features ofParkinson's disease(PD), includingconstipation, excessive daytime sleepiness, and symptoms ofdepression, new research suggests. ...
Prasinezumab, a monoclonal antibody that binds aggregated α-synuclein, is being investigated as a potential disease-modifying therapy in early-stage Parkinson’s disease. Although in the PASADENA phase 2 study, the primary endpoint (Movement Disorder So
Advanced-stage colorectal cancer in persons younger than 50 years not associated with longer duration of symptoms or time to diagnosis. Clin Gastroenterol Hepatol. 2017;15(5):728-737, e723.Google ScholarCrossref 83. Taggarshe D, Rehil N, Sharma S, Flynn JC, Damadi A. Colorectal cancer:...