一.总述 帕金森病(Parkinson Disease, PD)于1817年由英国医生James Parkinson首先描述,是一种缓慢进展的神经系统变性疾病,多见于中老年人。部分患者发病时年龄较小,称为早发性帕金森病(early-onset Parkinson Disease, EOPD),具有与典型PD不同的特点...
应该是late-onset Parkinson 迟发性帕金森 early-onser Parkinson 这个是早发性帕金森
The recent editorial1 supporting initial treatment of early onset Parkinson's disease with a dopamine agonist hinged in part on the demonstration2 in 268 patients that treatment of early onset Parkinson's disease with ropinirole alone or with supplementary levodopa/dopa decarboxylase inhibitor (benser...
3) Idiopathic Parkinson Disease 特发性帕金森病 1. The Clinical Analysis of Orthostatic Hypotension in Idiopathic Parkinson Disease and Multiple System Atrophy with Orthostatic Hypotension and the Study of IPD-OH and MSA-OH by ～1H-MRS and DWI; 直立性低血压在特发性帕金森病和伴有直立性低血压的...
Background:Several studies have compared early-onset Parkinson disease (EOPD) and late-onset Parkinson disease (LOPD) but most are not based on autopsy confirmed cases.Methods:We compared clinical and pharmacological profiles, time to reach irreversible Hoehn and Yahr (H&Y) Stage 3 and levodopa mo...
This cohort study of women in the Nurses’ Health Study II assesses the association of obesity and weight gain since early adulthood with early-onset
Alzheimer’s disease (AD) and Parkinson’s disease (PD), two common irreversible neurodegenerative diseases, share similar early stage syndromes, such as olfaction dysfunction. Yet, the potential comorbidity mechanism of AD and PD was not fully elucidate
是的，pubmed有号 Neuropsychiatr Dis Treat. 2013;9:1067-9. doi: 10.2147/NDT.S48455. Epub 2013 Aug 2.A Case of early onset Parkinson's disease after major stress.Zou K, Guo W, Tang G, Zheng B, Zheng Z.SourceNeurobiological Laboratory, People's Republic of China.Abstract...
Introduction Early -onset Parkinson's disease (EOPD) labels those cases with onset earlier than fifty. Although peculiarities emerged either in clinical or pathological features, EOPD is managed alike typical, late-onset PD. A customized approach would be, instead, better appropriate. Accordingly, ...
Neurodegeneration in Parkinson’s disease (PD) precedes diagnosis by years. Early neurodegeneration may be reflected in RNA levels and measurable as a biomarker. Here, we present the largest quantification of whole blood linear and circular RNAs (circRNA