帕金森病(Parkinson Disease, PD)于1817年由英国医生James Parkinson首先描述,是一种缓慢进展的神经系统变性疾病,多见于中老年人。部分患者发病时年龄较小,称为早发性帕金森病(early-onset Parkinson Disease, EOPD),具有与典型PD不同的特点。Tanner等...
Early-onset Parkinson's disease in a Chinese population: 99mTc-TRODAT-1 SPECT: Parkinson gene analysis and clinical study. Parkinsonism Relat Disord 2005;11:173-180.Shyu WC, Lin SZ, Chiang MF, et al. Early onset Parkinson's disease in a Chinese population: 99mTc-TRODAT-1 SPECT, Parkin ...
应该是late-onset Parkinson 迟发性帕金森 early-onser Parkinson 这个是早发性帕金森
For the analysis of late-onset CRC, early-onset CRC cases were censored at diagnosis. P for heterogeneity was calculated assuming a linear association between current BMI vs early-onset or late-onset CRC using a likelihood ratio test. Statistical significance was set as P ≤ .05 in 2-...
Background:Several studies have compared early-onset Parkinson disease (EOPD) and late-onset Parkinson disease (LOPD) but most are not based on autopsy confirmed cases.Methods:We compared clinical and pharmacological profiles, time to reach irreversible Hoehn and Yahr (H&Y) Stage 3 and levodopa mo...
2) sporadic Parkinson's disease(sPD) 散发性帕金森病例句>> 3) Idiopathic Parkinson Disease 特发性帕金森病 1. The Clinical Analysis of Orthostatic Hypotension in Idiopathic Parkinson Disease and Multiple System Atrophy with Orthostatic Hypotension and the Study of IPD-OH and MSA-OH by ～1H-MRS ...
Alzheimer’s disease (AD) and Parkinson’s disease (PD), two common irreversible neurodegenerative diseases, share similar early stage syndromes, such as olfaction dysfunction. Yet, the potential comorbidity mechanism of AD and PD was not fully elucidate
Neurodegeneration in Parkinson’s disease (PD) precedes diagnosis by years. Early neurodegeneration may be reflected in RNA levels and measurable as a biomarker. Here, we present the largest quantification of whole blood linear and circular RNAs (circRNA
Parkin analysis in early onset Parkinson's disease. Parkinsonism Relat. Disord. 14 (4), 326-333.Francesca S,Paola P,Michela Z,et al.Parkin analysis in early onset Parkinson’’s disease. Parkinsonism and Related Disorders . 2008Sironi F, Primignani P, Zini M, Tunesi S, Ruffmann C, ...
This systematic review and meta-analysis examines the frequency of presenting red flag signs and symptoms among individuals with early-onset colorectal