Alzheimer’s disease (AD), the most common type of dementia, affects an increasingly high number of individuals worldwide1,2. According to the amyloid cascade hypothesis, amyloid-β (Aβ)-species (e.g., monomers, oligomers, fibrils, and plaques) are major hallmarks of AD from early onset3...
Late-onset Alzheimer s disease (LOAD) is a complicated disease, associated with several factors. 晚发性阿尔茨海默病(LOAD)是一种多因子遗传病,其病因和发病机制至今还没有完全搞清楚。4) Late-onset Alzheimer's disease 晚发型阿尔茨海默病(LOAD)5...
told Science Popularization Times that some young patients with Alzheimer's disease have been detected earlier due to the advancement of detection methods and technology, but they are individual cases and do not necessarily mean early-onset Alzheimer's disease....
Alzheimer's disease (AD) in younger patients is associated with a higher prevalence of atypical symptoms. We examined neuropsychological performance according to age-at-onset. We assessed cognition in 172 patients with AD (81 early and 91 late onset) in five cognitive domains (memory, language, ...
See also: Alzheimer disease, late-onset Alzheimer disease. Farlex Partner Medical Dictionary © Farlex 2012 early-onset Alzheimer disease Alzheimer disease that occurs before the age of 65. See also: Alzheimer, Alois Medical Dictionary, © 2009 Farlex and Partners...
Early-onset Alzheimer's disease (EOAD) is a disorder with a dominantly inherited form, listed as being of significance for insurance by the Association of British Insurers. Mutations in the Presenilin-1 (PSEN-1) gene are responsible for a large proportion of cases. Gui & Macdonald (2002) ...
Brain computed tomographic scans of 60 patients with early-onset Alzheimer's disease (mean age, 60.7 years) were compared with those of age- and sex-matched control subjects. Computed tomographic analysis included standard ventricular measurements as well as subjective ratings of ventricular and sulcal...
Alzheimer's Disease (AD) represents the most common cause of dementia and is the leading cause of mortality in the elderly. The majority of cases are sporadic and occur after age 65, constituting late-onset AD. On the other hand, < 5% of all cases occur earlier than age 65 and, thereby...
Early-onset Alzheimer’s disease, also called younger onset Alzheimer’s disease, is an uncommon form of dementia which affects individuals younger than the age of 65.
Alzheimer's Research & Therapy All Volumes & Issues Open Access Early-onset dementia ISSN: 1758-9193 (Online) In this topical collection (2 articles) Review What can we learn from study of Alzheimer's disease in patients with Down syndrome for early-onset Alzheimer's disease in the ...