Importance of the field: Inflammatory bowel diseases are chronic inflammatory diseases that comprise of two forms – Crohn's disease (CD) and ulcerative colitis (UC) – characterized by aberrant responses to luminal bacteria in genetically susceptible individuals. Whereas inflammation is limited to the...
Growth in the drugs to treat Crohn's disease market is being hampered by considerable reimbursement limitations on biological agents, including Centocor's infliximab [Remicade], according to Decision Resources. Third-party payers in the US and Europe impose significant limitations on the use of ...
Remicade reduces the effects of a substance in the body that can cause inflammation. Remicade is used to treatrheumatoid arthritis, psoriatic arthritis,ankylosing spondylitisand severe or disabling plaque psoriasis in adults. Remicade is also used to treatulcerative colitisandCrohn's diseasein adults an...
Adalimumab may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. This has occurred mainly in teenagers and young men with Crohn's disease or ulcerative colitis. However, anyone with an inflammatory autoimmune disorder may have a higher risk of ...
(Jakinibs) in the treatment of rheumatologic disease demonstrates that intracellular signaling pathways can be targeted therapeutically to treat autoimmunity. Tofacitinib, the first rheumatologic Jakinib, is US Food and Drug Administration (FDA) approved for rheumatoid arthritis and is currently under ...
Dr. Paul DonohuePaul G. Donohue (STANDARD)
Crohn’s disease (CD) leads to a poor health-related quality of life (HRQoL). This review aimed to investigate the effect of biological agents and small-molecule drugs in improving the HRQoL of patients with moderate to severe CD. We adopted a systematic
benefit-risk;inflammatory bowel disease;patients;physicians 1. Introduction Crohn’s disease (CD) and ulcerative colitis (UC) are inflammatory bowel diseases (IBDs) with a remitting and relapsing course [1,2]. They are chronic diseases with a significant burden on patients’ quality of life. Ove...
Treanda (bendamustine) is used to treat chronic lymphocytic leukemia and non-Hodgkin lymphoma ... Reviews & ratings 1 Reviews View more Stelara Stelara (ustekinumab) is used to treat Crohn's disease, ulcerative colitis, plaque psoriasis, and ... ...
have immune system problems such as Crohn’s disease, ulcerative colitis, or lupus have received an organ transplant have liver disease have received or plan to receive a stem cell transplant that uses donor stem cells (allogeneic) have received radiation treatment to your chest area in the past...