疏风解毒胶囊 5.2 宣肺败毒颗粒 5.3 麻杏石甘汤 5.4 热炎宁合剂 5.5 小青龙汤 5.6 连花清瘟胶囊 5.7 喜炎平注射液 英文原文 Drożdżal S, Rosik J, Lechowicz K, et al. An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment. Drug Resist Updat. 2021.
2022年8月,来自美国圣约翰大学陈哲生教授、潍坊医学院的阎芳和房春燕在Drug Resistance Updates上发表了题为“Targeting feedback activation of signaling transduction pathways to overcome drug resistance in cancer”的综述,总结了介导AKT、ERK、STAT3、EGFR、FGFR和HER2/3信号通路反馈激活的因素以及增强抗肿瘤效果或克...
iNature 胃癌(Gastric cancer, GC)的新辅助治疗是GC综合治疗中不可或缺的一部分。然而部分进展期GC患者在接受化疗联合免疫治疗的新辅助治疗方案时表现出原发性耐药,并有部分患者在使用药物一段时间后产生获得性耐药。这表现出GC对化疗联...
近日国际学术期刊Drug Resistance Updates发表了张灏教授团队的Targeting undruggable phosphatase overcomes trastuzumab resistance by inhibiting multi-oncogenic kinases文章,报道了他们建立的抗体导向递送RNA激活药物的新途径,克服磷酸酶“不能成药...
Drug Resist Updat | 组蛋白乳酸化修饰介导膀胱癌顺铂耐药性 膀胱癌(Bladder Cancer,BCa)是全球十大最常见的癌症之一。其中肌层浸润性病例的5年生存率仅为20-40%,且近50%在3年内出现转移。以顺铂为基础的化疗是转移性膀胱癌的主要治疗方法,数据表明大多数患者最终会复发并产生耐药性。研究发现,表观遗传调控在...
Mapping cryptic binding sites of drug targets to overcome drug resistance. January 01, 2023 [MEDLINE Abstract] Deoxycytidine kinase (dCK) inhibition is synthetic lethal with BRCA2 deficiency. January 01, 2023 [MEDLINE Abstract] Aeromonas spp. from hospital sewage act as a reservoir of genes resist...
Purinergic signalling in cancer therapeutic resistance: From mechanisms to targeting strategies. January 01, 2023 [MEDLINE Abstract] Elevated NOX4 promotes tumorigenesis and acquired EGFR-TKIs resistance via enhancing IL-8/PD-L1 signaling in NSCLC. ...
5.4 热炎宁合剂 5.5 小青龙汤 5.6 连花清瘟胶囊 5.7 喜炎平注射液 英文原文 Drożdżal S, Rosik J, Lechowicz K, et al. An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment. Drug Resist Updat. 2021.
5.4 热炎宁合剂 5.5 小青龙汤 5.6 连花清瘟胶囊 5.7 喜炎平注射液 英文原文 Drożdżal S, Rosik J, Lechowicz K, et al. An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment. Drug Resist Updat. 2021.