DRB1 DNA was amplified by PCR with DR52 group specific primer sets and 29 sequence specific oligonecleotide probes were used. The second allele of these donors fall into different amplification groups, therefore does not confound typing. The hybridization pattern of GN 070 and GN 071 reveals ...
*Dr Heung-Bum Oh 388-1, Pungnap-dong Songpa-gu Seoul 138-736 Korea Tel: 82 2 3010 4505 Fax: 82 2 478 0884 e-mail: hboh@amc.seoul.kr Publication History Issue published online: 9 MAR 2011 Article first published online: 9 MAR 2011 ...
Genetic Polymorphism of HLA DR in a Scottish Population of Patients with Pars Planitis: PurposeHuman leucocyte antigen (HLA) class II influences the immunological susceptibility for a variety of diseases including many types of non-infectious ... H K.,Greiner,WL D.,... - 《European Journal of...
Naturally processed peptides from two disease-resistance-associated HLA-DR13 alleles show related sequence motifs and the effects of the dimorphism at position 86 of the HLA-DR beta chain Proc. Natl. Acad. Sci. U. S. A., 92 (1995), pp. 6567-6571 ...
HLA DR13-DQ5/单倍型 连锁不平衡患者,男,37岁,因多发性骨髓瘤,于2003年3月及4 月,携其父母妻女儿及2位同胞兄弟,来本中心要求做骨髓 移植HLA配型. 1 材料与方法 1.1 试剂与仪器 美国Pel Freez公司DNA快速提取试剂 盒;美国Pel Freez公司ABDRDQSSPUniTray分型板[聚 合酶链反应 序列特异性引物(PCR SSPdoi:...
Interestingly, human leucocyte antigen (HLA)-DR13 show a strong association with the clearance of HBV [odds ratio (OR) = 0.04, 95% confidence interval (CI) = 0.00–0.26, corrected P-value ( Pc) = 0.0008] similar to reports from several ethic groups. ...
DR13ReplicationJuvenile idiopathic arthritis (JIA) is the commonest rheumatic disease of childhood. Uveitis is the commonest eye complication of JIA, potentially leading to eye surgery and/or visual loss. JIA is a complex genetic trait with well-established HLA-DRB1 associations. The aim of this...
Sequencing of the DR52-associated PCR-amplified DNA from the subject was performed in both directions using two clones. Nucleotide sequences of DRB113VHT confirmed that this allele is identical to DRB11301 except for the substitution of a single nucleotide, changing codon 67 from ATC (Ile) to...
Abstract: Three novel HLA class H alleles (DRB1*1333, DRB1*O426, DRB5*0109) are described here. The 3 novel alleles were initially detected as previously unidentified SSO hybridization patterns using the CANTYPE reverse hybridization assay. Sequences were determined by cloning/sequencing. DRB1*...
Human Leukocyte Antigen and Systemic Sclerosis in Japanese: The Sign of the Four Independent Protective Alleles, DRB1*13:02, DRB1*14:06, DQB1*03:01, and DPB1*02:01. PLoS One. 2016; 11(4):e0154255. https://doi.org/10.1371/journal.pone.0154255 PMID: 27116456....