Renal survival was favorable in the AAV group compared with both the anti-GBM group (P < 0.01) and the double double-positive groups (P < 0.01). Patients who were double positive tended to have better renal survival than those who were single positive with anti-GBM disease, although this ...
There was one grade 5 AE (pneumonia in the placebo arm) which was not considered related to treatment. The most common treatment-related AEs (TRAEs; deemed related to any of the study treatments) were diarrhoea, fatigue and mucosal inflammation (Additional file 1: Table S2). There was one ...
Pneumocystis pneumonia—sulfamethoxazole-trimethoprim, dapsone, or aerosolized pentamidine End points The composite primary end point was assessed in hospitalized patients over days 0–7 after transplantation (Figure 2). The five primary composite end point components were (a) fever (≥38.5°C), (b)...
Common causes of neonatal distress include respiratory distress syndrome, transient tachypnea of newborns, pneumothorax, and pneumonia. Neonatal pulmonary hypertension (PH) may rapidly develop secondary to parenchymal lung disease. Neonatal respiratory failure affects 2% of all live births and is described ...
Objective response rate OS: Overall survival PD: Progressive disease PD-1: Programmed cell death protein-1 PD-L1: Programmed death-ligand 1 PFS: Progression-free survival PR: Partial response RECIST v1.1: Response Evaluation Criteria in Solid Tumors version 1.1 SAE: Serious adverse eve...
Intrauterine growth re- striction (IUGR) permanently alters fetal metabolism to enable survival in restricted environment. When a child with IUGR is born and raised in the environment rich in high–cal- ories diet, which are becoming more frequent in middle–income and even ...
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease with poor prognosis and short median survival [1]. The etiology remains not completely clear [2]. With a low prevalence rate, some scholars consider it as a rare disease [3]. In China, it has also been included ...
Although BCG has been shown to induce a trained immune response against H7N9 in mouse models, subsequent evaluations show that the immune response is not significantly associated with clinical survival, clinical scores or pulmonary inflammation137. The effectiveness of the NSEs of BCG is based on ...
There was a slight increase in pulmonary adverse events, but only 1 patient had a severe adverse event (pneumonia) in the rhGM-CSF group, in comparison with 3 such patients in the placebo group. The most common adverse events leading to discontinuation of rhGM-CSF were not associated with ...
Alteration of fatty acid profiles in different pulmonary surfactant phospholipids in acute respiratory distress syndrome and severe pneumonia. Am J Respir Crit Care Med. 2001;163(1):95–100. Article CAS PubMed Google Scholar Beitler JR, Malhotra A, Thompson BT. Ventilator-induced lung injury. ...