Background Rapid eye movement sleep behavior disorder (RBD) is highly comorbid with Parkinson's disease (PD). Emerging evidence suggests that dopamine-replacement therapies (DRTs) for PD may modify the course of RBD, yet the nature of the association between DRTs and RBD remains unclear. To ...
A direct antidepressant effect has been reported for certain dopaminergic medications used in the treatment of Parkinson's disease (PD). To examine whether dopaminergic medications may exert differential effects on mood in early PD. We analyzed prospectively-collected 5-year data on 405 early, drug-...
PARKINSON'S diseaseDOPAMINE agentsThis article explores the challenges posed when ensuring the effective management of patients with Parkinson's in the secondary care setting. The evidence base around the appropriate timing and administration of medications is explored and highlights key themes in the ...
Objective To explore the change in prescribing practices for dopaminergic medications in Parkinson''s disease between 2010 and 2017. Methods Data were collected from the Parkinson''s Foundation Quality Improvement Initiative registry. Baseline characteristics were compared between the 2010 and 2017 cohorts...
(2009). Dopaminergic medication effects of the speech of individuals with Parkinson''s disease. Journal of Medical Speech-Language Pathology, 17, 125144.Source of funding and disclosure of interest: This study was partially supported by Grant 1-R03-DC007066 from the National Institute on Deafness...
A direct antidepressant effect has been reported for certain dopaminergic medications used in the treatment of Parkinson's disease (PD). To examine whether dopaminergic medications may exert differential effects on mood in early PD. We analyzed prospectively-collected 5-year data on 405 early, drug-...
Dopaminergic medications are used as first-line treatment for Parkinson's disease (PD). In 1999, a case series was published describing 9 patients who took dopamine agonists (pramipexole or ropinirole) and experienced sudden irresistible sleep attacks. Sleep attacks have subsequently been reported with...
OBJECTIVES: Impaired proprioception has been previously reported in patients with Parkinson's disease. It was hypothesised that dopaminergic medications transiently depress proprioception, with amplification of adventitious movements as a result. This study tested for effects on proprioception of dopaminergic ...
O'Suilleabhain P, Bullard J, Dewey RB. Proprioception in Parkinson's dis- ease is acutely depressed by dopaminergic medications. J Neurol Neurosurg Psychiatry 2001; 71: 607-10.O'Suilleabhain, P., Bullard, J., Dewey, R.B., 2001. Proprioception in Parkinson's disease is acutely depressed...
Background: Somatosensory abnormalities contribute to the pathophysiology of Parkinson's disease (PD). The goal of this study was to identify abnormalities in the tactile-evoked activation of the somatosensory and motor cortices in PD, and in a sensorimotor circuit that traverses both of these ...