5). Fig. 4: Structure of the portal-scaffold complex in the B-capsid. a Superposition of the C1 density map of the portal vertex region (transparent gray) with the composite cryoEM map of the portal and the portal-bound scaffold in the B-capsid that was assembled from reconstructions as...
5). It is important to note that Waddington and contemporaries developed epigenetic concepts in an era of tremendous discovery about the basic structure and composition of DNA.Footnote 3 In 1941, George Beadle (1903–1989) and Edward Tatum (1909–1975) developed what later was called the “one...
2024年9月2日,南京大学陈加余课题组在Nature Chemistry杂志发表了题为“Chemoproteomic profiling unveils binding and functional diversity of endogenous proteins that interact with endogenous triplex DNA”的研究论文,首次系统性揭示了内...
2b). The plasmid was separated into 3, 4, 5 or 6 fragments using PCR, and these fragments were treated with DpnI to remove the circular template. The control samples were prepared by using a similar amount of input DNA without supplementation with the XthA enzyme. The negative colonies ...
FIT-039 是一种选择性和 ATP 竞争性的口服活性 CDK9 抑制剂,对CKD9/cyclin T1的IC50为 5.8 μM。它抑制HSV-1(IC50为 0.69 μM),HSV-2,人腺病毒和人CMV 的复制。它可抑制耐药性HSV 和其他 DNA 病毒,是有前途的抗病毒药物。 规格价格库存数量 1 mg ¥ 158 现货 5 mg ¥ 368 现货 10 mg ...
Keywords:DNA;Double Helix Structure;Franklin;X-ray Diffraction 在十九世纪60年代,剑桥中对女性科学家的歧视尤为严重,男性科学家不仅认为女性无法在学术上取得重大的成就,甚至不愿意让女性科学家在高级休息室里就餐,这对于富兰克林等女性科学家而言,无疑是让她们与科学界形成了一道无形的屏障,妨碍她们与其他科学家的交...
DNA is the hereditary material in humans and almost all other organisms. It is essential for maintaining accurate transmission of genetic information. In t
声明: 本网站大部分资源来源于用户创建编辑，上传，机构合作，自有兼职答题团队，如有侵犯了你的权益，请发送邮箱到feedback@deepthink.net.cn 本网站将在三个工作日内移除相关内容,刷刷题对内容所造成的任何后果不承担法律上的任何义务或责任
The structure, function and evolution of proteins that bind DNA and RNA Proteins that bind both DNA and RNA typify the ability of a single gene product to perform multiple functions. Such DNA- and RNA-binding proteins (DRBPs) h... WH Hudson,EA Ortlund - 《Nature Reviews Molecular Cell Bio...
Electron-microscopic images of the free protein show a globular tetrahedral structure. Binding of poly(desoxythymidylic acid) (poly(dT)) leads to a reduction of the tryptophan fluorescence of the protein up to 96%. Fluorescence titrations with poly(dT) show apparent binding-site sizes of 50-...