In this paper, the viability of mononuclear leukocytes with different variants of C-262T polymorphism in the catalase gene (CC, CT, TT) was examined under oxidative stress induced by hydrogen peroxide. It was f
Jakobsson J, Karypidis H, Johansson JE, Roh HK, Rane A, and Ekstrom L (2004) A functional C-G polymorphism in the CYP7B1 promoter region and its different distribution in Orientals and Caucasians. Pharmacogenomics J 4:245-250.J. Jakobsson, H. Karypidis, J.E. Johansson, H.K. Roh,...
The FokI rs2228570 polymorphism in exon 2 at the 5′ end of the VDR gene is called a start codon polymorphism. When the “T” allele is present, the VDR protein is three amino acids longer, whereas the “C” allele produces a shorter VDR protein linked to a 1.7-fold higher transcripti...
Furthermore, genetic variants that modulate GRN expression, such as the GRNrs5848 polymorphism, have been associated with an increased risk of AD24,25. There are multiple evidences that support that glia is activated in synucleinopathies26. In particular, activated microglia targeting dopamine nigra...
This plasticity mediated by D2 receptors is thought to strengthen the indirect pathway, which could prevent the execution of incorrect motor plans (Frank, 2005). Consequently, we hypothesized that a polymorphism in the DRD1 gene (rs686) that has been shown to influence receptor density affects ...
pcr qpcr pcr followed by restriction fragment length polymorphism (pcr-rflp) pcr for microarray analysis what is microarray analysis:microarray analysis looks at what genes areturned onduring certain times with or without treatment (experimental conditions), and it can simultaneously evaluate thousands ...
Chromosomal microarray analysis (CMA) Single nucleotide polymorphism-chromosomal microar- ray analysis was performed using Affymetrix CytoScan 750 K Array chips and Affymetrix Chromosome Analy- sis Suite (ChAS) software, and the detected structure was analyzed according to the latest ACMG guidelines ...
Previous studies demonstrated that H37Rv belonged to the T clade and the single-nucleotide polymorphism cluster group SCG-6b [ 24 , 25 ]. The virulence of H37Rv has been demonstrated in different animal models. For example, SCID mice infected with H37Rv usually survive for a mean time of 30 ...
This study investigated the effects of dietary protein levels under various heat stress (HS) conditions on the growth performance and stress parameters in Korean native beef calves. Male calves (n = 40; initial BW = 202.2 ± 3.31 k
(CD4+T-cells) and reduce the polymorphism of HLA-DR molecules in the population, this epitope has been added to the vaccine structure with the GPGPG linker. In addition, to enhance and heighten the long-term immune response, the adjuvant 50S ribosomal protein L7/L12 (rpIL) (Locus RL7_...