Depression is the most frequent psychiatric symptom in Huntington's disease (HD), which often presents already in the early stage of the disease and may even precede motor symptoms. Symptoms like sadness, loss of interest or pleasure, feelings of guilt or low self-worth, disturbed sleep or ...
摘要: •Disease stage predicted depression and general distress in HD.•A linear trend for depression across disease stage was found.•No sex differences in distress were apparent in HD across any disease stage.关键词:Huntington disease Depression Anxiety Sex Disease stage HADS ...
Huntington's disease (HD) is an extraordinary disorder that usually strikes when individuals are in the prime of their lives, as was the case for the influential 20th century musician Woody Guthrie. HD demonstrates the exceptionally fine line between life and death in such ‘genetic diseases’, ...
Paralimbic frontal lobe hypometabolism in depression associated with Huntington's disease 来自 Semantic Scholar 喜欢 0 阅读量: 47 作者:HS Mayberg,SE Starkstein,CE Peyser,J Brandt,SE Folstein 摘要: We measured regional cerebral using 2-[18F]--2-deoxy-D-and emission tomography in depressed and ...
In neurodegenerative diseases, such as Huntington’s disease (HD), PD, AD, and also psychiatric conditions, i.e., depression, anxiety, or schizophrenia, the decreased levels of cellular and plasma vitamin C and increased free radicals are observed, so their scavengers may exhibit therapeutic effec...
meaning there are probably many different genes, with each exerting small effects, rather than a single gene leading to disease risk. The genetics of depression, like most psychiatric disorders, is not as simple as that of purely genetic diseases, such as Huntington's chorea or cystic fibrosis....
Parkinson's disease, Huntington's chorea, schizophrenia, anxiety, depression, manic depression, psychoses, epilepsy, obsessive compulsive disorders, mood disorders, migraine, Alzheimer's disease, age related cognitive decline, mild cognitive impairment, sleep disorders, eating disorders, anorexia, bulimia,...
In particular, 5-HT2-selective and 5-HT6 selective ligands have been identified as potentially useful in the treatment of certain CNS disorders such as Parkinson's disease, Huntington's disease, anxiety, depression, manic depression, psychoses, epilepsy, obsessive compulsive disorders, mood disorders...
Recent studies showed the potential therapeutic effects of ROCK inhibitor and ROCK signaling in the treatment of neurodegenerative diseases, such as Alzheimer’s disease [14], [15], Parkinson’s disease [16], [17], Huntington’s disease [18], [19], Amyotrophic lateral sclerosis [20] and ...
Delusion and depression in huntington disease as a neuropsychiatry paradigmGalva, J.Noguero Alegre, A.European Psychiatry