Dementia is increasingly being recognized in cases of Parkinson's disease (PD); such cases are termed PD dementia (PDD). The spread of fibrillar α-synuclein (α-syn) pathology from the brainstem to limbic and neocortical structures seems to be the strongest neuropathological correlate of emergi...
Dementia is common in Parkinson's disease patients. When dementia is present it complicates management especially in the elderly Parkinsonian. And dementia associated with Parkinson's disease is significantly more common in the late-onset (compared with early-onset) case. The dementia of Parkinson's...
ResearchOpen Access12 May 2025npj Parkinson's Disease Volume: 11, P: 124 News and Comment Mind over microplastics — what we still don’t know Microplastics have been observed in human brain tissue for the first time, and higher levels were associated with dementia. However, important questions...
The combination of dementia and parkinsonism is common and distressing, and dementia associated with Parkinson's disease (PDD) and dementia with Lewy bodies (DLB) are the most common causes. By definition, in PDD, dementia develops after more than one year with parkinsonism, whereas in DLB, dem...
Parkinson's disease dementia (PDD) Frontotemporal disorders (FTD) This is a group of neurodegenerative brain disorders that primarily affect the frontal and temporal lobes of your brain. Your frontal lobe partly controls your personality, decision-making, movement, and ability to smell and speak. Ch...
Other articles where Parkinson disease dementia is discussed: dementia with Lewy bodies: …Lewy bodies is related to Parkinson disease dementia (PDD), in that both are associated with the accumulation of so-called Lewy bodies—abnormal deposits of a prot
Dementia is also present in other degenerative brain diseases, includingPick diseaseandParkinson disease. Another form of dementia, known aslimbic-predominant age-related TDP-43 encephalopathy (LATE), closely resembles Alzheimer disease. Although LATE is also marked by thedeteriorationof memory and cognit...
Parkinson's disease dementia (PDD) Frontotemporal disorders (FTD) This is a group of neurodegenerative brain disorders that primarily affect the frontal and temporal lobes of your brain. Your frontal lobe partly controls your personality, decision-making, movement, and ability to smell and speak. Ch...
Parkinson's disease and Alzheimer's disease as disorders of the isodendritic core Br Med J (1981) Aj Lees, Cognitive deficits in Parkinson's disease In: J. Gispen, J. Traber (Eds), Aging and the brain Vol II,... GcCelesiaet al. ...
Parkinson's disease with dementia and dementia with Lewy body disease: two syndromes, the same disease? Psychogeriatrics, 6: S30-S34Sellal, F.: Parkinson's disease with dementia and dementia with Lewy body disease: two syndromes, the same disease? Psychogeriatrics 6 (2006) 30-34...