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when using EPG parsimonious matrices, the network method (FastUnfold) provided the most significant enrichment and segregation of ontology terms. This was a particular feature of the combination of FastUnfold with parsimonious matrices as applying FastUnfold to the total correlation matrix without parsimo...
To this end, we allowed cells expressing mRFP-Stx6 and GFP-Stx13 to internalize either labeled Tfn or labeled CTxB and then monitored segregation of SNAREs and cargoes with time-lapse imaging (Fig.3b–d) (note that for CTxB, Vero cells were used due to weak internalization in HeLa cells...