De-Novo-Cancer网络恶性肿瘤;癌化 网络释义 1. 恶性肿瘤 在器官移植后的恶性肿瘤 (De Novo cancer)发生率约6-10%,且某些癌症(Kaposi’s sarcoma, skin cancer…) 发生机率甚至比正常 …www.transplant.org.tw|基于1 个网页 2. 癌化 ...致癌机转内有约20%的机率是由平坦型的大肠黏膜直接癌化(De Novo ...
Cancers in solid organ recipients may be classified as donor transmitted,donor derived,de novo or recurrent.The risk of donor-transmitted cancer is very low and can be reduced by careful screening of the donor but cannot be abolished and,in the United Kingdom series is less than 0.03%.For ...
To investigate the mutated gene expression signatures, we tested GSEA curated cancer hallmarks enriched for the stage-specific mutated genes (Fig.6d). As expected, mutated genes were enriched in pathways associated with melanoma development and progression, including the p53 pathway, epithelial to mesen...
After about70 years with no significant progress, the landscape for men with de novo metastatic prostate cancer has changed dramatically in the past 4 years, with statistically significant and highly clinically meaningful survival improvement reported from multiple phase III trials when abiraterone (Yonsa...
5 For cancer cells, metabolic adaptations leading to increased synthesis of nucleotides by de novo biosynthesis pathways are emerging as key alterations driving cancer growth. Genes involved in de novo nucleotide biosynthetic pathway are up-regulated in high-speed proliferation cells, such as dividing ...
support either emergence of pre-existing resistant clones orde novoevolution as the predominant mechanism of acquired resistance in lung cancer.(Nature medicine) 三篇文章从用法到含义,对于de novo的理解都是不一样的。第一段话明确指出:固有耐药,原发耐药,de novo三者是一个含义;而第二段和第三段中的de...
owing to the secular trend of delaying parenthood to later maternal age at childbirth, especially in Western countries. In addition, normal variation in reproductive lifespan is causally associated with the risk of a wide range of disease outcomes, such as type 2 diabetes mellitus, cancer and imp...
The scientist attempts to look for one medicine to treat cancer, but seeks the reagent to result in the human to be a problem. [translate] agiven all these results 给出所有这些结果 [translate] aDe novo methylases add new methyl groups, and of course, demethylases remove unwanted methyl ...
We present a stochastic network model of metastasis spread for de novo metastatic breast cancer, composed of tumor to metastasis (primary seeding) and metastasis to metastasis spread (secondary seeding), parameterized using the SEER (Surveillance, Epidemiology, and End Results) database. The model pr...