QUANTITATIVE PHOSPHOPROTEOMICS IDENTIFIES ALTERATIONS OF DOUBLECORTIN-LIKE KINASE 1 (DCLK1) IN NEURAL PROGENITOR CELL DIFFERENTIATIONQuantitative phosphoproteomicsNeurosphere differentiationLC-MS/MSDCLK1BioIDOligodendrocytes are the myelinating cells of the central nervous system and originate from neural stem ...
et al. Altered expression of a putative progenitor cell marker DCAMKL1 in the rat gastric mucosa in regeneration, metaplasia and dysplasia. BMC Gastroenterol 10, 65, doi: 10.1186/1471-230X-10-65 (2010). 34. May, R. et al. Identification of a novel putative pancreatic stem/progenitor cell...
Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentia‑ tion in the embryonic and adult lung. J Mol Cell Biol. 2015;7(1):35–47. 56. Kango-Singh M, Singh A. Regulation of organ size: insights from the drosophila hippo signaling pathway. Dev Dyn. 2009;238(...
PanINs and IPMNs are the two most common precursor lesions that can progress to invasive pancreatic ductal adenocarcinoma (PDA). DCLK1 has been identified as a biomarker of progenitor cells in PDA progressed from PanINs. To explore the potential role of DCLK1-expressing cells in the genesis of...
Neurospheres are free-floating clusters of cells. They are typically generated from mouse or rat cortical tissue-derived cells which, after supplementation of the culture medium with bFGF and EGF, give rise to neurospheres that can be maintained in a progenitor state under cell culture conditions ...
mM sodium acetate buffer pH 4.0, 1% (v/v) DMSO final, in the presence 10 µM of the moderate affinity compound FMF-03-149-01 (IC50~400 nM)28to help to stabilise the kinase domain during immobilsiation at low pH. A blank immobilisation was performed on the reference flow cell....
We and others have recently reported that autocrine PG up-regulates expression of stem-cell-markers DCLK1/CD44/LGR5 (Gastro, 2011; IJC, 2012). Two major isoforms of DCLK1 (DCLK1-S, DCLK1-L) have been reported in neuroprogenitor......
et al. Altered expression of a putative progenitor cell marker DCAMKL1 in the rat gastric mucosa in regeneration, metaplasia and dysplasia. BMC Gastroenterol 10, 65, 10.1186/1471-230X-10-65 (2010). Article CAS ADS PubMed PubMed Central Google Scholar May, R. et al. Identification of a...