Previous studies showed that whereas a combination of the senolytic drugs dasatinib and quercetin (D + Q) reduced NAFLD in mice, D + Q lacked efficacy in removing doxorubicin-induced 尾-gal-positive senescent cells in human HCC xenografted mice. Whether D + Q has an effect on the age-...
Senolytics are a class of drugs that selectively remove senescent cells. Dasatinib and quercetin have been discovered, and their combination has shown various anti-ageing effects. The SAMP10 mouse strain is a model of brain ageing. Here, we investigated
GeroScience (2023) 45:2835–2850 https://doi.org/10.1007/s11357-023-00843-0 ORIGINAL ARTICLE Sexual dimorphic metabolic and cognitive responses of C57BL/6 mice to Fisetin or Dasatinib and quercetin cocktail oral treatment Yimin Fang · David Medina · Robert Stockwell ·...
Enhancing oral bioavailability of quercetin using novel soluplus polymeric micelles Nanoscale Res. Lett., 9 (2014), p. 684, 10.1186/1556-276X-9-684 View in ScopusGoogle Scholar [24] M. Linn, E.-M. Collnot, D. Djuric, K. Hempel, E. Fabian, K. Kolter, C.-M. Lehr Soluplus® as...
Cell Commun Signal (2021) 19:44 https://doi.org/10.1186/s12964-021-00731-0 SHORT REPORT Open Access Mild exacerbation of obesity‑ and age‑dependent liver disease progression by senolytic cocktail dasatinib + quercetin Marco Raffaele1*† , Kristina Kovacovicova1†, ...