通过通路分析,本研究发现三七抗炎作用与癌症信号通路(pathways in cancer)、细胞因子受体相互作用(cytokine-cytokine receptor Interaction)、突触细胞黏附分子信号通路(cell adhesion molecules,CAMs)等密切相关。 4.3.1癌症信号通路癌症信号通路包含了与肿瘤形成15个...
基于KEGG通路富集分析的薏苡仁不同成分对Cytokine-cytokine receptor interaction靶基因作用,目的:探讨薏苡仁不同组分对脾虚湿阻证大鼠细胞因子-细胞因子受体相互作用的影响及关键靶点。方法:以薏苡仁不同组分作用于脾虚湿阻证大鼠,通过其肠全基因表达谱测定,对筛选的差异基
基于KEGG通路富集分析的薏苡仁不同成分对Cytokine-cytokine receptor interaction靶基因作用 脾虚湿阻证细胞因子-细胞因子受体相互作用薏苡仁趋化因子肿瘤坏死因子目的:探讨薏苡仁不同组分对脾虚湿阻证大鼠细胞因子-细胞因子受体相互作用的影响及关键靶点.方法:以薏苡仁不同组分作用于脾虚湿阻证大鼠,通过其肠全基因表达谱测定...
信号通路(Kegg pathway):43种蛋白广泛分布在多种通路中,其中Cytokine-cytokine receptor interaction通路有30种蛋白,JAK-STAT signaling pathway通路16种蛋白,IL-17 signaling pathway 15种蛋白,还和Th17 cell differentiation、NOD-like receptor signaling pathway等通路相关。 从Olink官方网站中可下载43个assay 列表: htt...
(Cytokinecytokine receptor interaction)通路中被显著富集;egln家族基因在HIF-1信号通路广泛表达;说明低氧应激可能诱导梭鲈鳃的先天性免疫反应,激活HIF-1,吞噬体,细胞... 吉宇丹 - 上海海洋大学 被引量: 0发表: 2023年 Integrated Analysis of Transcriptomics to Identify Hub Genes in Primary Sjgren's Syndrome ...
Cytokines are released by various cells in the body, usually in response to an activating stimulus, and they induce responses through binding to specific receptors on the cell surface of target cells.
Cytokine-cytokine receptor interaction Cytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell growth, differentiation, cell death, angiogenesis, and development and re...
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Cytokine and/or cytokine receptor engineering is being widely investigated to safely and effectively modulate cytokine activity for therapeutic benefit. IL-2 in particular has been extensively engineered, to create IL-2 variants that differentially exhibit activities on regulatory T cells to potentially ...
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